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Sodium pyruvate is a salt of the conjugate anion form of pyruvic acid, known as pyruvate. It is commonly added to cell culture media as an additional source of energy, but may also have protective effects against hydrogen peroxide. This was reported by Giandomenico et al. and has been confirmed by several independent groups. Along with having antioxidant properties and energy producing effects, sodium pyruvate has the ability to cross the blood-brain barrier and is used in several studies on brain injury because of these characteristics.

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dbo:abstract
  • بيروفات الصوديوم مركب كيميائي له الصيغة C3H3NaO3 يضاف عادةً إلى مستحضرات أوساط الخلايا كمصدر إضافي للطاقة. (ar)
  • Natria piruvato, piruvato de natrio aŭ H3C3NaO3 estas organika kombinaĵo, rezultanta el reakcio inter piruvata acido kaj natria hidroksido, peranto en la sukera metabolo kaj enzima karbohidrata degradiĝo (aŭ alkohola fermentigo) kie ĝi konvertiĝas al acetaldehido pere de karboksilazo. En la muskoloj, piruvata acido (derivata el glikogeno) reduktiĝas al laktata acido okaze de penego. Ĝi estas foriganto de liberradikaloj kaj elmontriĝas kiel protektanto kontraŭ apoptozo kaŭzata de hidrogena peroksido. (eo)
  • Sodium pyruvate is a salt of the conjugate anion form of pyruvic acid, known as pyruvate. It is commonly added to cell culture media as an additional source of energy, but may also have protective effects against hydrogen peroxide. This was reported by Giandomenico et al. and has been confirmed by several independent groups. Due to pyruvate being an intermediate in many pathways for metabolism including glycolysis, sodium pyruvate has been used in many experiments involving cell cultures to provide more energy. In adipocytes it was found that sodium pyruvate promoted increased uptake of insulin-mediated glucose. In the body, one way in which sodium pyruvate provides energy to cells is through pyruvate conversion to acetyl-CoA which then can enter the TCA cycle which produces energy and is linked to other energy producing processes. Along with having antioxidant properties and energy producing effects, sodium pyruvate has the ability to cross the blood-brain barrier and is used in several studies on brain injury because of these characteristics. (en)
  • ピルビン酸ナトリウム(ピルビンさんナトリウム、Sodium pyruvate)は、ピルビン酸の共役塩基の塩の1つである。 (ja)
  • Il piruvato di sodio è il sale di sodio dell'acido piruvico. A temperatura ambiente si presenta come un solido cristallino bianco. Viene comunemente aggiunto ai terreni di coltura cellulare come fonte aggiuntiva di energia, ma può anche avere effetti protettivi contro il perossido di idrogeno. Poiché il piruvato è un intermedio in molte vie del metabolismo, inclusa la glicolisi, il piruvato di sodio è stato utilizzato in molti esperimenti che coinvolgono colture cellulari per fornire più energia. Negli adipociti si è scoperto che il piruvato di sodio promuoveva un maggiore assorbimento del glucosio insulino-mediato. Nel corpo, un modo in cui il piruvato di sodio fornisce energia alle cellule è attraverso la conversione del piruvato in acetil-CoA, producendo energia. Il piruvato di sodio ha la capacità di attraversare la barriera ematoencefalica e viene utilizzato in diversi studi sulle lesioni cerebrali a causa di queste caratteristiche. (it)
  • 丙酮酸鈉(Sodium pyruvate)常被用於細胞培養的培養基,作為能量的來源。此外,Giandomenico等人發現,丙酮酸鈉也能保護細胞免於受到過氧化氫的損害,此功能已被許多其他團隊證實。 (zh)
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  • Sodium 2-oxopropanoate (en)
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  • Sodium pyruvate.png (en)
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  • Pyruvate-3D-balls.png (en)
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  • Sodium-3D.png (en)
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  • Ball-and-stick model of the pyruvate anion (en)
dbp:imagenamer
  • The sodium cation (en)
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  • Sodium pyruvate (en)
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  • Sodium 2-oxopropanoate (en)
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  • بيروفات الصوديوم مركب كيميائي له الصيغة C3H3NaO3 يضاف عادةً إلى مستحضرات أوساط الخلايا كمصدر إضافي للطاقة. (ar)
  • Natria piruvato, piruvato de natrio aŭ H3C3NaO3 estas organika kombinaĵo, rezultanta el reakcio inter piruvata acido kaj natria hidroksido, peranto en la sukera metabolo kaj enzima karbohidrata degradiĝo (aŭ alkohola fermentigo) kie ĝi konvertiĝas al acetaldehido pere de karboksilazo. En la muskoloj, piruvata acido (derivata el glikogeno) reduktiĝas al laktata acido okaze de penego. Ĝi estas foriganto de liberradikaloj kaj elmontriĝas kiel protektanto kontraŭ apoptozo kaŭzata de hidrogena peroksido. (eo)
  • ピルビン酸ナトリウム(ピルビンさんナトリウム、Sodium pyruvate)は、ピルビン酸の共役塩基の塩の1つである。 (ja)
  • 丙酮酸鈉(Sodium pyruvate)常被用於細胞培養的培養基,作為能量的來源。此外,Giandomenico等人發現,丙酮酸鈉也能保護細胞免於受到過氧化氫的損害,此功能已被許多其他團隊證實。 (zh)
  • Sodium pyruvate is a salt of the conjugate anion form of pyruvic acid, known as pyruvate. It is commonly added to cell culture media as an additional source of energy, but may also have protective effects against hydrogen peroxide. This was reported by Giandomenico et al. and has been confirmed by several independent groups. Along with having antioxidant properties and energy producing effects, sodium pyruvate has the ability to cross the blood-brain barrier and is used in several studies on brain injury because of these characteristics. (en)
  • Il piruvato di sodio è il sale di sodio dell'acido piruvico. A temperatura ambiente si presenta come un solido cristallino bianco. Viene comunemente aggiunto ai terreni di coltura cellulare come fonte aggiuntiva di energia, ma può anche avere effetti protettivi contro il perossido di idrogeno. Il piruvato di sodio ha la capacità di attraversare la barriera ematoencefalica e viene utilizzato in diversi studi sulle lesioni cerebrali a causa di queste caratteristiche. (it)
rdfs:label
  • بيروفات الصوديوم (ar)
  • Natria piruvato (eo)
  • Piruvato di sodio (it)
  • ピルビン酸ナトリウム (ja)
  • Sodium pyruvate (en)
  • 丙酮酸鈉 (zh)
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  • Sodium pyruvate (en)
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