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- In molecular biology, Small nucleolar RNA sR8 is a non-coding RNA belonging to the C/D box class of snoRNAs. sR8, along with other C/D box snoRNAs, performs 2′-O-methylation of ribose on a target strand of ribosomal RNA. Targeting is achieved through the C and D box components, which are short sections of conserved sequences, as well as C'/D' boxes (internal equivalents of the C and D boxes). These sequences base-pair with nucleotides in the target rRNA to direct their methylation. sR8 RNA operates alongside protein components in a ribonucleoprotein (RNP) complex. sR8 is able to guide the methylation of targets found within structured stem-loops, which implies that a component of the complex is able to unwind such structures. (en)
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- 4520 (xsd:nonNegativeInteger)
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- sR8 consensus sequence (en)
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- Small nucleolar RNA sR8 (en)
- sR8 (en)
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- In molecular biology, Small nucleolar RNA sR8 is a non-coding RNA belonging to the C/D box class of snoRNAs. sR8, along with other C/D box snoRNAs, performs 2′-O-methylation of ribose on a target strand of ribosomal RNA. Targeting is achieved through the C and D box components, which are short sections of conserved sequences, as well as C'/D' boxes (internal equivalents of the C and D boxes). These sequences base-pair with nucleotides in the target rRNA to direct their methylation. (en)
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- Small nucleolar RNA sR8 (en)
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