About: Sink condition

An Entity of Type: Thing, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

In pharmaceutics, sink condition is a term mostly related to the dissolution testing procedure. It means using a sheer volume of solvent, usually about 5 to 10 times greater than the volume present in the saturated solution of the targeted chemical (often the API, and sometimes the excipients) contained in the dosage form being tested.

Property Value
dbo:abstract
  • In pharmaceutics, sink condition is a term mostly related to the dissolution testing procedure. It means using a sheer volume of solvent, usually about 5 to 10 times greater than the volume present in the saturated solution of the targeted chemical (often the API, and sometimes the excipients) contained in the dosage form being tested. During the dissolution testing, "sink condition" is a mandatory requirement, otherwise when the concentration begins to get too close to the saturation point, even though the total soluble amount still remains constant, the dissolution rate will gradually begin to reduce in significant amounts, enough to corrupt the test results. . (en)
dbo:wikiPageID
  • 50210529 (xsd:integer)
dbo:wikiPageLength
  • 2452 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID
  • 953124664 (xsd:integer)
dbo:wikiPageWikiLink
dbp:wikiPageUsesTemplate
dcterms:subject
rdfs:comment
  • In pharmaceutics, sink condition is a term mostly related to the dissolution testing procedure. It means using a sheer volume of solvent, usually about 5 to 10 times greater than the volume present in the saturated solution of the targeted chemical (often the API, and sometimes the excipients) contained in the dosage form being tested. (en)
rdfs:label
  • Sink condition (en)
owl:sameAs
prov:wasDerivedFrom
foaf:isPrimaryTopicOf
is dbo:wikiPageRedirects of
is dbo:wikiPageWikiLink of
is foaf:primaryTopic of
Powered by OpenLink Virtuoso    This material is Open Knowledge     W3C Semantic Web Technology     This material is Open Knowledge    Valid XHTML + RDFa
This content was extracted from Wikipedia and is licensed under the Creative Commons Attribution-ShareAlike 3.0 Unported License