About: Signaling lymphocytic activation molecule

An Entity of Type: protein, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Signaling lymphocytic activation molecule (SLAM) is a family of genes. Homophilic binding between SLAMs is involved in cell-to-cell adhesion during antigen presentation. Signaling lymphocytic activation molecules are a CD2-related surface receptor expressed by activated phagocytes, T helper cells, and platelets. SLAMs have a variety of functions, including enhancing T cellular proliferation by stimulating IL-4 and IFN-gamma production. SLAM family (SLAMF) receptors can interact directly with microbes, which can cause phagocytic cells to migrate to the area. SLAMF activation can trigger SLAM-associated protein (SAP) activation and a defective SAP can cause X-linked lymphoproliferative syndrome (XLP).

thumbnail
Property Value
dbo:abstract
  • Les SLAM (pour « Signaling lymphocytic activation molecule ») constituent une famille de protéines. Les différents membres en sont : * SLAMF1 (CD150) * (CD48) * (CD229, LY9) * (CD244) * (CD84) * (CD352) * SLAMF7 (CD319) * (CD353) * (fr)
  • Signaling lymphocytic activation molecule (SLAM) is a family of genes. Homophilic binding between SLAMs is involved in cell-to-cell adhesion during antigen presentation. Signaling lymphocytic activation molecules are a CD2-related surface receptor expressed by activated phagocytes, T helper cells, and platelets. SLAMs have a variety of functions, including enhancing T cellular proliferation by stimulating IL-4 and IFN-gamma production. SLAM family (SLAMF) receptors can interact directly with microbes, which can cause phagocytic cells to migrate to the area. SLAMF activation can trigger SLAM-associated protein (SAP) activation and a defective SAP can cause X-linked lymphoproliferative syndrome (XLP). (en)
dbo:symbol
  • SLAM
dbo:thumbnail
dbo:wikiPageID
  • 16033981 (xsd:integer)
dbo:wikiPageLength
  • 10423 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID
  • 1097415933 (xsd:integer)
dbo:wikiPageWikiLink
dbp:interpro
  • IPR010407 (en)
dbp:membranomeFamily
  • 164 (xsd:integer)
dbp:name
  • Signaling lymphocytic activation molecule (en)
dbp:pfam
  • PF06214 (en)
dbp:symbol
  • SLAM (en)
dbp:wikiPageUsesTemplate
dcterms:subject
gold:hypernym
rdf:type
rdfs:comment
  • Les SLAM (pour « Signaling lymphocytic activation molecule ») constituent une famille de protéines. Les différents membres en sont : * SLAMF1 (CD150) * (CD48) * (CD229, LY9) * (CD244) * (CD84) * (CD352) * SLAMF7 (CD319) * (CD353) * (fr)
  • Signaling lymphocytic activation molecule (SLAM) is a family of genes. Homophilic binding between SLAMs is involved in cell-to-cell adhesion during antigen presentation. Signaling lymphocytic activation molecules are a CD2-related surface receptor expressed by activated phagocytes, T helper cells, and platelets. SLAMs have a variety of functions, including enhancing T cellular proliferation by stimulating IL-4 and IFN-gamma production. SLAM family (SLAMF) receptors can interact directly with microbes, which can cause phagocytic cells to migrate to the area. SLAMF activation can trigger SLAM-associated protein (SAP) activation and a defective SAP can cause X-linked lymphoproliferative syndrome (XLP). (en)
rdfs:label
  • SLAM (protéine) (fr)
  • Signaling lymphocytic activation molecule (en)
owl:sameAs
prov:wasDerivedFrom
foaf:depiction
foaf:isPrimaryTopicOf
is dbo:wikiPageDisambiguates of
is dbo:wikiPageRedirects of
is dbo:wikiPageWikiLink of
is foaf:primaryTopic of
Powered by OpenLink Virtuoso    This material is Open Knowledge     W3C Semantic Web Technology     This material is Open Knowledge    Valid XHTML + RDFa
This content was extracted from Wikipedia and is licensed under the Creative Commons Attribution-ShareAlike 3.0 Unported License