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- Shredding refers to the process in bioinformatics of taking assembled gene sequences and disassembling them into short sequences of usually 500 to 750 base pairs (bp). This is generally done for the purpose of taking the short shredded sequences and reapplying various analysis and bioinformatic techniques. Being able to cut DNA samples and then run them through gel electrophoresis to study each strand in order to help find cures for diseases or illnesses is also another purpose. The most common tool or enzyme used to shred DNA into fragments is CAS9. Clustered regularly interspaces short palindromic repeats(CRISPR) - Cas9 allows genetic material to be either altered, removed or added at specific locations. CRISPR-Cas 9 consists of guide RNA (gRNA) and the enzyme(Cas9). This enzyme is able to cut DNA the exactly as wanted without making a mistake. There are also many other enzymes that help with shredding such as CASX or CAS3. CAS3 is a shredding tool but is not as accurate as CAS9 and may lead to random DNA strands being deleted. (en)
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- Shredding refers to the process in bioinformatics of taking assembled gene sequences and disassembling them into short sequences of usually 500 to 750 base pairs (bp). This is generally done for the purpose of taking the short shredded sequences and reapplying various analysis and bioinformatic techniques. Being able to cut DNA samples and then run them through gel electrophoresis to study each strand in order to help find cures for diseases or illnesses is also another purpose. (en)
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- Shredding (disassembling genomic data) (en)
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