About: Selenoneine

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Selenoneine is a selenium containing ergothioneine derivative where the selenium (Se) atom replaces a sulfur atom. It can be systematically named as (2-selenyl-Nα,Nα,Nα-trimethyl-L-histidine or 3-(2-hydroseleno-1H-imidazol-5-yl)-2-(trimethylammonio)propanoate). It is found in the blood of bluefin tuna, and other sea dwelling animals like turtles, mackerel, beluga, and giant petrels. It is an antioxidant, combining with reactive oxygen species and boosting the action of GPx1. In air selenoneine is easily oxidised to a dimer containing a (Se-Se).

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  • Selenoneine is a selenium containing ergothioneine derivative where the selenium (Se) atom replaces a sulfur atom. It can be systematically named as (2-selenyl-Nα,Nα,Nα-trimethyl-L-histidine or 3-(2-hydroseleno-1H-imidazol-5-yl)-2-(trimethylammonio)propanoate). It is found in the blood of bluefin tuna, and other sea dwelling animals like turtles, mackerel, beluga, and giant petrels. It is an antioxidant, combining with reactive oxygen species and boosting the action of GPx1. Selenoneine is produced by microorganisms using enzymes that form a selenium-carbon bond. Humans that eat fish have selenoneine in their blood. About half of selenium is in the form of selenoneine. Selenoneine inhibits angiotensin-converting enzyme. In vertebrates, selenoneine is transported into cells using OCTN1. Selenoneine reacts with methyl mercury to form a mercury tetraselenoate complex, which degrades to tiemannite, a mercury selenide. This is a mechanism used to detoxify mercury in marine vertebrates. A related derivative, Se-methylselenoneine is found in lesser quantities in mackerel, sardine and tuna. In air selenoneine is easily oxidised to a dimer containing a (Se-Se). (en)
  • セレノネイン (英語: Selenoneine) とは、魚類に含まれる有機セレン化合物でエルゴチオネインのチオケトン基がセレノケトン基に置き換わったイミダゾール化合物。2010年に独立行政法人 水産総合研究センターの山下由美子、山下倫明によって報告された新規化合物質である。特にマグロ類、カジキ類、サバ類などの回遊魚の血合肉や血液に多く含まれる。 (ja)
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  • セレノネイン (英語: Selenoneine) とは、魚類に含まれる有機セレン化合物でエルゴチオネインのチオケトン基がセレノケトン基に置き換わったイミダゾール化合物。2010年に独立行政法人 水産総合研究センターの山下由美子、山下倫明によって報告された新規化合物質である。特にマグロ類、カジキ類、サバ類などの回遊魚の血合肉や血液に多く含まれる。 (ja)
  • Selenoneine is a selenium containing ergothioneine derivative where the selenium (Se) atom replaces a sulfur atom. It can be systematically named as (2-selenyl-Nα,Nα,Nα-trimethyl-L-histidine or 3-(2-hydroseleno-1H-imidazol-5-yl)-2-(trimethylammonio)propanoate). It is found in the blood of bluefin tuna, and other sea dwelling animals like turtles, mackerel, beluga, and giant petrels. It is an antioxidant, combining with reactive oxygen species and boosting the action of GPx1. In air selenoneine is easily oxidised to a dimer containing a (Se-Se). (en)
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  • セレノネイン (ja)
  • Selenoneine (en)
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