About: Segrosome

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Segrosomes are protein complexes that ensure accurate segregation (partitioning) of plasmids or chromosomes during bacterial cell division. Just as higher forms of life have evolved a complex mitotic apparatus to partition duplicated DNA during cell division, bacteria require a specialized apparatus to partition their duplicated DNA. In bacteria, segrosomes perform the function similar to that performed by mitotic spindle. Therefore, segrosomes can be thought of as minimalist spindles.

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  • Segrosomes are protein complexes that ensure accurate segregation (partitioning) of plasmids or chromosomes during bacterial cell division. Just as higher forms of life have evolved a complex mitotic apparatus to partition duplicated DNA during cell division, bacteria require a specialized apparatus to partition their duplicated DNA. In bacteria, segrosomes perform the function similar to that performed by mitotic spindle. Therefore, segrosomes can be thought of as minimalist spindles. Segrosomes are usually composed of three basic components- the DNA (plasmid or chromosome) that needs to be segregated into daughter cells, a motor protein that provides the necessary physical forces for accomplishing the segregation and a DNA binding protein that connects the DNA and the motor protein, to form the complete segrosome complex. (en)
  • I segrosomi sono complessi proteici che veicolano la segregazione di plasmidi e cromosomi durante la divisione cellulare batterica.Nei batteri il segrosoma svolge la funzione analoga a quella eseguita dal fuso mitotico nelle cellule eucariotiche (strutturalmente molto più complesso).I segrosomi sono solitamente costituiti da tre componenti base: * il materiale genetico (plasmide o cromosoma) che devono essere suddivisi nelle cellule figlie * una proteina motore che genera le forze meccaniche necessarie per realizzare la separazione * una proteina che lega il DNA e lo mette in comunicazione con le proteine motore per formare il complesso del segrosoma. (it)
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  • Segrosomes are protein complexes that ensure accurate segregation (partitioning) of plasmids or chromosomes during bacterial cell division. Just as higher forms of life have evolved a complex mitotic apparatus to partition duplicated DNA during cell division, bacteria require a specialized apparatus to partition their duplicated DNA. In bacteria, segrosomes perform the function similar to that performed by mitotic spindle. Therefore, segrosomes can be thought of as minimalist spindles. (en)
  • I segrosomi sono complessi proteici che veicolano la segregazione di plasmidi e cromosomi durante la divisione cellulare batterica.Nei batteri il segrosoma svolge la funzione analoga a quella eseguita dal fuso mitotico nelle cellule eucariotiche (strutturalmente molto più complesso).I segrosomi sono solitamente costituiti da tre componenti base: (it)
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  • Segrosoma (it)
  • Segrosome (en)
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