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- Die massenspektrometrische Probenvorbereitung dient der Optimierung einer Probe für die Analyse in einem Massenspektrometer.Diese haben, je nach Ionisationsverfahren, unterschiedliche Anforderungen an Volumen, Konzentration und Zusammensetzung der Analyt-Lösung. (de)
- Sample preparation for mass spectrometry is used for the optimization of a sample for analysis in a mass spectrometer (MS). Each ionization method has certain factors that must be considered for that method to be successful, such as volume, concentration, sample phase, and composition of the analyte solution. Quite possibly the most important consideration in sample preparation is knowing what phase the sample must be in for analysis to be successful. In some cases the analyte itself must be purified before entering the ion source. In other situations, the matrix, or everything in the solution surrounding the analyte, is the most important factor to consider and adjust. Often, sample preparation itself for mass spectrometry can be avoided by coupling mass spectrometry to a chromatography method, or some other form of separation before entering the mass spectrometer. In some cases, the analyte itself must be adjusted so that analysis is possible, such as in protein mass spectrometry, where usually the protein of interest is cleaved into peptides before analysis, either by in-gel digestion or by proteolysis in solution. (en)
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| rdfs:comment
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- Die massenspektrometrische Probenvorbereitung dient der Optimierung einer Probe für die Analyse in einem Massenspektrometer.Diese haben, je nach Ionisationsverfahren, unterschiedliche Anforderungen an Volumen, Konzentration und Zusammensetzung der Analyt-Lösung. (de)
- Sample preparation for mass spectrometry is used for the optimization of a sample for analysis in a mass spectrometer (MS). Each ionization method has certain factors that must be considered for that method to be successful, such as volume, concentration, sample phase, and composition of the analyte solution. Quite possibly the most important consideration in sample preparation is knowing what phase the sample must be in for analysis to be successful. In some cases the analyte itself must be purified before entering the ion source. In other situations, the matrix, or everything in the solution surrounding the analyte, is the most important factor to consider and adjust. Often, sample preparation itself for mass spectrometry can be avoided by coupling mass spectrometry to a chromatography m (en)
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