About: SKA2

An Entity of Type: protein, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Spindle and kinetochore-associated protein 2 is a protein that in humans is encoded by the SKA2 gene found in chromosome 17. SKA2 is a part of a spindle and kinetochore associated complex also including SKA1 and which is responsible for onset of the anaphase in mitosis by regulating chromosomal segregation.

Property Value
dbo:abstract
  • Spindle and kinetochore-associated protein 2 is a protein that in humans is encoded by the SKA2 gene found in chromosome 17. SKA2 is a part of a spindle and kinetochore associated complex also including SKA1 and which is responsible for onset of the anaphase in mitosis by regulating chromosomal segregation. SKA2 may function as a prognostic gene marker for identifying lung cancer as well as a proposed biomarker for suicidal tendencies and post-traumatic stress disorders. The SKA2 gene contains one single-nucleotide polymorphism (SNP) rs7208505 located in the 3' UTR. This genetic variant containing a cytosine (existing in the less common allele) instead of thymine along with epigenetic modification (such as DNA methylation) is correlated with suicidal tendencies and post-traumatic stress. (en)
dbo:wikiPageID
  • 43465647 (xsd:integer)
dbo:wikiPageLength
  • 12376 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID
  • 1044811302 (xsd:integer)
dbo:wikiPageWikiLink
dbp:altnames
  • Family with Sequence Similarity 33. Member A, FAM33A, Spindle and KT Associated 2, Protein FAM33A (en)
dbp:arm
  • q (en)
dbp:band
  • 22 (xsd:integer)
dbp:chromosome
  • 17 (xsd:integer)
dbp:ensembl
  • ENSG00000182628 (en)
dbp:entrezgene
  • 348235 (xsd:integer)
dbp:hgncid
  • 28006 (xsd:integer)
dbp:name
  • Spindle and Kinetochore Associated Complex Subunit 2 (en)
dbp:omim
  • 616674 (xsd:integer)
dbp:symbol
  • SKA2 (en)
dbp:uniprot
  • Q8WVK7 (en)
dbp:wikiPageUsesTemplate
dct:subject
gold:hypernym
rdf:type
rdfs:comment
  • Spindle and kinetochore-associated protein 2 is a protein that in humans is encoded by the SKA2 gene found in chromosome 17. SKA2 is a part of a spindle and kinetochore associated complex also including SKA1 and which is responsible for onset of the anaphase in mitosis by regulating chromosomal segregation. (en)
rdfs:label
  • SKA2 (en)
owl:sameAs
prov:wasDerivedFrom
foaf:isPrimaryTopicOf
is dbo:wikiPageRedirects of
is dbo:wikiPageWikiLink of
is foaf:primaryTopic of
Powered by OpenLink Virtuoso    This material is Open Knowledge     W3C Semantic Web Technology     This material is Open Knowledge    Valid XHTML + RDFa
This content was extracted from Wikipedia and is licensed under the Creative Commons Attribution-ShareAlike 3.0 Unported License