Rugby sevens competitions at the 2022 South American Games in Asuncion, Paraguay were held between 7 and 9 October 2022 at the Estadio Héroes de Curupayty located within the cluster in Luque, a sub-venue outside Asunción. Two medal events were scheduled to be contested: a men's and women's tournament. A total of 192 athletes (84 athletes–7 teams for men and 108 athletes–9 teams for women) competed in the events. Both tournaments were open competitions, however, players must be at least 17 years old at the start of the tournament.