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Ribonuclease T (RNase T, exonuclease T, exo T) is a ribonuclease enzyme involved in the maturation of transfer RNA and ribosomal RNA in bacteria, as well as in DNA repair pathways. It is a member of the DnaQ family of exonucleases and non-processively acts on the 3' end of single-stranded nucleic acids. RNase T is capable of cleaving both DNA and RNA, with extreme sequence specificity discriminating against cytosine at the 3' end of the substrate.

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dbo:abstract
  • Ribonuclease T (RNase T, exonuclease T, exo T) is a ribonuclease enzyme involved in the maturation of transfer RNA and ribosomal RNA in bacteria, as well as in DNA repair pathways. It is a member of the DnaQ family of exonucleases and non-processively acts on the 3' end of single-stranded nucleic acids. RNase T is capable of cleaving both DNA and RNA, with extreme sequence specificity discriminating against cytosine at the 3' end of the substrate. (en)
  • Рибонуклеаза T (РНКаза T, экзонуклеаза T, exo T) — фермент рибонуклеаза, действующая при созревании транспортных и рибосомных РНК у бактерий, а также в процессах репарации ДНК. Рибонуклеаза T входит в семейство экзонуклеаз . Она действует на 3'-конец одноцепочечных нуклеиновых кислот и может расщеплять как ДНК, так и РНК с высокой специфичностью дискриминируя остаток цитозин на 3'-конце субстрата. (ru)
dbo:symbol
  • rnt
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  • 45256144 (xsd:integer)
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  • 9941 (xsd:nonNegativeInteger)
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  • 1044706714 (xsd:integer)
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dbp:caption
  • A ribonuclease T dimer in complex with DNA , from PDB ID 3NH1. (en)
dbp:interpro
  • IPR013520 (en)
dbp:name
  • Ribonuclease T (en)
dbp:pfam
  • PF00929 (en)
dbp:smart
  • SM00479 (en)
dbp:symbol
  • rnt (en)
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rdfs:comment
  • Ribonuclease T (RNase T, exonuclease T, exo T) is a ribonuclease enzyme involved in the maturation of transfer RNA and ribosomal RNA in bacteria, as well as in DNA repair pathways. It is a member of the DnaQ family of exonucleases and non-processively acts on the 3' end of single-stranded nucleic acids. RNase T is capable of cleaving both DNA and RNA, with extreme sequence specificity discriminating against cytosine at the 3' end of the substrate. (en)
  • Рибонуклеаза T (РНКаза T, экзонуклеаза T, exo T) — фермент рибонуклеаза, действующая при созревании транспортных и рибосомных РНК у бактерий, а также в процессах репарации ДНК. Рибонуклеаза T входит в семейство экзонуклеаз . Она действует на 3'-конец одноцепочечных нуклеиновых кислот и может расщеплять как ДНК, так и РНК с высокой специфичностью дискриминируя остаток цитозин на 3'-конце субстрата. (ru)
rdfs:label
  • Ribonuclease T (en)
  • Рибонуклеаза T (ru)
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