About: Renzapride

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Renzapride is a prokinetic agent and antiemetic which acts as a full 5-HT4 agonist and partial 5-HT3 antagonist. It also functions as a 5-HT2B antagonist and has some affinity for the 5-HT2A and 5-HT2C receptors. Renzapride was being developed by Alizyme plc of the United Kingdom. In May 2016, EndoLogic LLC, a US-based pharmaceutical and medical device company, acquired the US and worldwide patent rights to Renzapride. Endologic confirmed the cardiac safety of renzapride through a “Thorough QTc” study and sold the rights to Atlantic Healthcare plc in 2019, a specialist pharmaceutical company.

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dbo:abstract
  • رينزابرايد (بالإنجليزية: Renzapride)‏ ويعرف بالاسم التجاري رينزابرايد (بالإنجليزية: Renzapride)‏ هو دواء يساعد على تنظيم حركة الأمعاء، ويستخدم لعلاج التهاب المعدة، والارتجاع المعدي المريئي، عسر الهضم، أعراض القولون العصبي. (ar)
  • Renzapride is a prokinetic agent and antiemetic which acts as a full 5-HT4 agonist and partial 5-HT3 antagonist. It also functions as a 5-HT2B antagonist and has some affinity for the 5-HT2A and 5-HT2C receptors. Renzapride was being developed by Alizyme plc of the United Kingdom. In May 2016, EndoLogic LLC, a US-based pharmaceutical and medical device company, acquired the US and worldwide patent rights to Renzapride. Endologic confirmed the cardiac safety of renzapride through a “Thorough QTc” study and sold the rights to Atlantic Healthcare plc in 2019, a specialist pharmaceutical company. Atlantic Healthcare is focusing on the development of renzapride for the management of gastrointestinal (GI) motility in a number of rare diseases, including systemic scleroderma and cystic fibrosis, both of which are associated with chronic GI motility problems and for which there are no approved therapies. (en)
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  • 109872-41-5
  • 112727-80-7
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  • 289753
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  • 6H0SNK4GNT
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  • رينزابرايد (بالإنجليزية: Renzapride)‏ ويعرف بالاسم التجاري رينزابرايد (بالإنجليزية: Renzapride)‏ هو دواء يساعد على تنظيم حركة الأمعاء، ويستخدم لعلاج التهاب المعدة، والارتجاع المعدي المريئي، عسر الهضم، أعراض القولون العصبي. (ar)
  • Renzapride is a prokinetic agent and antiemetic which acts as a full 5-HT4 agonist and partial 5-HT3 antagonist. It also functions as a 5-HT2B antagonist and has some affinity for the 5-HT2A and 5-HT2C receptors. Renzapride was being developed by Alizyme plc of the United Kingdom. In May 2016, EndoLogic LLC, a US-based pharmaceutical and medical device company, acquired the US and worldwide patent rights to Renzapride. Endologic confirmed the cardiac safety of renzapride through a “Thorough QTc” study and sold the rights to Atlantic Healthcare plc in 2019, a specialist pharmaceutical company. (en)
rdfs:label
  • رينزابرايد (ar)
  • Renzapride (en)
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