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- El Método de Reed y Muench es el procedimiento empleado para calcular puntos finales de 50% en la o de bacterias intracelulares obligadas, como parte de pruebas de . La distancia proporcional entre dos diluciones, en la cual se encuentran el punto final de 50% se obtiene mediante el % mortalidad mayor de 50%-50%/% de mortalidad mayor de 50%-% de mortalidad menor de 50% Entonces el logaritmo negativo del título de LD sub 50 será igual al Log negativo de la dilución mayor al 50% de mortalidad+la distancia proporcional. (es)
- See article above for overview of 50% endpoints and comparison with other methods of calculating 50% endpoints. The Reed–Muench method is a simple method for determining 50% endpoints in experimental biology, that is, the concentration of a test substance that produces an effect of interest in half of the test units. Examples include LD50 (the median lethal dose of a toxin or pathogen), EC50 and IC50 (half maximal effective or inhibitory concentration, respectively, of a drug), and TCID50 (50% tissue culture infectious dose of a virus). The reason for using 50% endpoints is that many dose-response relationships in biology follow a logistic function that flattens out as it approaches the minimal and maximal responses, so it is easier to measure the concentration of the test substance that produces a 50% response. (en)
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- El Método de Reed y Muench es el procedimiento empleado para calcular puntos finales de 50% en la o de bacterias intracelulares obligadas, como parte de pruebas de . La distancia proporcional entre dos diluciones, en la cual se encuentran el punto final de 50% se obtiene mediante el % mortalidad mayor de 50%-50%/% de mortalidad mayor de 50%-% de mortalidad menor de 50% Entonces el logaritmo negativo del título de LD sub 50 será igual al Log negativo de la dilución mayor al 50% de mortalidad+la distancia proporcional. (es)
- See article above for overview of 50% endpoints and comparison with other methods of calculating 50% endpoints. The Reed–Muench method is a simple method for determining 50% endpoints in experimental biology, that is, the concentration of a test substance that produces an effect of interest in half of the test units. Examples include LD50 (the median lethal dose of a toxin or pathogen), EC50 and IC50 (half maximal effective or inhibitory concentration, respectively, of a drug), and TCID50 (50% tissue culture infectious dose of a virus). (en)
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- Método de Reed y Muench (es)
- Reed–Muench method (en)
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