dbo:abstract
|
- الإجهاد الاختزالي هو النظير المغاير للإجهاد التأكسدي, حيث يكون من المتوقع لمستقبلات الإلكترون أن تكون مختزلة (تم اختزالها). يمكن أن يحدث بسبب أخذ كميات مفرطة من الجلوتاثيون, ويمكن أن تساهم في سمية الخلايا. (ar)
- Reductive stress is the counterpart to oxidative stress, where electron acceptors are expected to be mostly reduced. It can be caused by excess amounts of glutathione, and can contribute to cytotoxicity. Although different organelles may each have a different redox status, through probing for factors such as glutathione and H2O2, it was determined that reductive stress is present in the endoplasmic reticulum of senescent cells. Reductive stress is significant in the aging process of a cell and when ER oxidation status is elevated, cellular aging is slowed. In particular, when reductive stress is increased, it may result in many downstream effects such as increased apoptosis, decreased cell survival, and mitochondrial dysfunction—all of which need to be properly regulated to ensure that the needs of the cell are met. Reductive stress has even been suggested to lead to higher probability of cardiomyopathy in humans. This has also been mysteriously linked to the abundant presence of heat shock protein (Hsp) 27, suggesting that high levels of Hsp27 induce can induce cardiomyopathy .Reductive stress is present in many diseases with abnormalities such as the increase of reducing equivalents, resulting in issues such as hypoxia-induced oxidative stress. (en)
- 환원 스트레스(영어: reductive stress)는 산화 스트레스에 대응하는 개념으로 전자수용체가 대부분 환원됨으로 인해 발생하는 스트레스이다. 환원 스트레스는 과량의 글루타티온으로 인해 발생할 수 있으며, 세포 독성에 기여할 수 있다. (ko)
|
dbo:wikiPageID
| |
dbo:wikiPageLength
|
- 3736 (xsd:nonNegativeInteger)
|
dbo:wikiPageRevisionID
| |
dbo:wikiPageWikiLink
| |
dbp:wikiPageUsesTemplate
| |
dcterms:subject
| |
gold:hypernym
| |
rdf:type
| |
rdfs:comment
|
- الإجهاد الاختزالي هو النظير المغاير للإجهاد التأكسدي, حيث يكون من المتوقع لمستقبلات الإلكترون أن تكون مختزلة (تم اختزالها). يمكن أن يحدث بسبب أخذ كميات مفرطة من الجلوتاثيون, ويمكن أن تساهم في سمية الخلايا. (ar)
- 환원 스트레스(영어: reductive stress)는 산화 스트레스에 대응하는 개념으로 전자수용체가 대부분 환원됨으로 인해 발생하는 스트레스이다. 환원 스트레스는 과량의 글루타티온으로 인해 발생할 수 있으며, 세포 독성에 기여할 수 있다. (ko)
- Reductive stress is the counterpart to oxidative stress, where electron acceptors are expected to be mostly reduced. It can be caused by excess amounts of glutathione, and can contribute to cytotoxicity. Although different organelles may each have a different redox status, through probing for factors such as glutathione and H2O2, it was determined that reductive stress is present in the endoplasmic reticulum of senescent cells. Reductive stress is significant in the aging process of a cell and when ER oxidation status is elevated, cellular aging is slowed. In particular, when reductive stress is increased, it may result in many downstream effects such as increased apoptosis, decreased cell survival, and mitochondrial dysfunction—all of which need to be properly regulated to ensure that the (en)
|
rdfs:label
|
- إجهاد اختزالي (ar)
- 환원 스트레스 (ko)
- Reductive stress (en)
|
owl:sameAs
| |
prov:wasDerivedFrom
| |
foaf:isPrimaryTopicOf
| |
is dbo:wikiPageWikiLink
of | |
is foaf:primaryTopic
of | |