About: Rabconnectin-3A

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Rabconnectin-3A (Rbcn-3A) or DmX (Drosophila melanogaster X-gene) is a gene located on the X chromosome in Drosophila and encodes for the relatively large WD-repeat protein, rabconnectin-3A. Rabconnectin-3A is involved in Notch signalling by regulating the vacuolar proton pump V-ATPase. DmX is a highly conserved gene and is widely found in insects and mammals. Two orthologs of DmX exist in humans, and DMXL2, the latter of which codes for the synaptic protein rabconnectin-3α. Its name comes from the fact that it binds the Ras-related protein Rab3 (human RAB3A).

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  • Rabconnectin-3A (Rbcn-3A) or DmX (Drosophila melanogaster X-gene) is a gene located on the X chromosome in Drosophila and encodes for the relatively large WD-repeat protein, rabconnectin-3A. Rabconnectin-3A is involved in Notch signalling by regulating the vacuolar proton pump V-ATPase. DmX is a highly conserved gene and is widely found in insects and mammals. Two orthologs of DmX exist in humans, and DMXL2, the latter of which codes for the synaptic protein rabconnectin-3α. Its name comes from the fact that it binds the Ras-related protein Rab3 (human RAB3A). (en)
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  • Rabconnectin-3A (en)
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  • Drosophila melanogaster (en)
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  • Rbcn-3A (en)
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  • Q24593 (en)
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  • Rabconnectin-3A (Rbcn-3A) or DmX (Drosophila melanogaster X-gene) is a gene located on the X chromosome in Drosophila and encodes for the relatively large WD-repeat protein, rabconnectin-3A. Rabconnectin-3A is involved in Notch signalling by regulating the vacuolar proton pump V-ATPase. DmX is a highly conserved gene and is widely found in insects and mammals. Two orthologs of DmX exist in humans, and DMXL2, the latter of which codes for the synaptic protein rabconnectin-3α. Its name comes from the fact that it binds the Ras-related protein Rab3 (human RAB3A). (en)
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  • Rabconnectin-3A (en)
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