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In enzymology, a pyruvate oxidase (EC 1.2.3.3) is an enzyme that catalyzes the chemical reaction pyruvate + phosphate + O2 acetyl phosphate + CO2 + H2O2 The 3 substrates of this enzyme are pyruvate, phosphate, and O2, whereas its 3 products are , CO2, and H2O2.

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dbo:abstract
  • La pyruvate oxydase est une oxydoréductase qui catalyse la réaction : pyruvate + phosphate + O2 phosphate d'acétyle + CO2 + H2O2. Cette enzyme utilise le FAD et le TPP comme cofacteurs. Le FAD est réduit en FADH2 par deux mésomères carbanion/énamine de la 2-hydroxyéthyl-thiamine pyrophosphate (AcTPP) puis oxydé par une molécule d'oxygène pour donner du peroxyde d'hydrogène H2O2 tandis que l'AcTPP est clivé par phosphorolyse pour donner du phosphate d'acétyle et du TPP. (fr)
  • In enzymology, a pyruvate oxidase (EC 1.2.3.3) is an enzyme that catalyzes the chemical reaction pyruvate + phosphate + O2 acetyl phosphate + CO2 + H2O2 The 3 substrates of this enzyme are pyruvate, phosphate, and O2, whereas its 3 products are , CO2, and H2O2. This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with oxygen as acceptor. The systematic name of this enzyme class is pyruvate:oxygen 2-oxidoreductase (phosphorylating). Other names in common use include pyruvic oxidase, and phosphate-dependent pyruvate oxidase. This enzyme participates in pyruvate metabolism. It has 2 cofactors: FAD, and Thiamin diphosphate. (en)
  • La piruvato ossidasi è un enzima appartenente alla classe delle ossidoreduttasi, che catalizza la seguente reazione: piruvato + fosfato + O2 ⇄ acetil fosfato + CO2 + H2O2 L'enzima è una flavoproteina (FAD) che richiede tiamina difosfato. Due equivalenti riducenti sono trasferiti dal carbanione del 2-idrossietil-tiamina-difosfato all'adiacente cofattore flavinico, generando 2-acetil-tiamina difosfato (AcThDP) e flavina ridotta. Il FADH2 è riossidato dall'O2 per generare H2O2, mentre il FAD ed il AcThDP sono riconvertiti dall'acetil fosfato e dalla tiamina pirofosfato. (it)
  • ピルビン酸オキシダーゼ(pyruvate oxidase)は、ピルビン酸代謝酵素の一つで、次の化学反応を触媒する酸化還元酵素である。 ピルビン酸 + リン酸 + O2 アセチルリン酸 + CO2 + H2O2 反応式の通り、この酵素の基質はピルビン酸とリン酸と酸素、生成物はと二酸化炭素と過酸化水素である。補因子としてFADとチアミンピロリン酸を用いる。 組織名はpyruvate:oxygen 2-oxidoreductase (phosphorylating)で、別名にpyruvic oxidase, phosphate-dependent pyruvate oxidaseがある。 (ja)
dbo:ecNumber
  • 1.2.3.3
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  • pyruvate oxidase (en)
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rdfs:comment
  • La pyruvate oxydase est une oxydoréductase qui catalyse la réaction : pyruvate + phosphate + O2 phosphate d'acétyle + CO2 + H2O2. Cette enzyme utilise le FAD et le TPP comme cofacteurs. Le FAD est réduit en FADH2 par deux mésomères carbanion/énamine de la 2-hydroxyéthyl-thiamine pyrophosphate (AcTPP) puis oxydé par une molécule d'oxygène pour donner du peroxyde d'hydrogène H2O2 tandis que l'AcTPP est clivé par phosphorolyse pour donner du phosphate d'acétyle et du TPP. (fr)
  • La piruvato ossidasi è un enzima appartenente alla classe delle ossidoreduttasi, che catalizza la seguente reazione: piruvato + fosfato + O2 ⇄ acetil fosfato + CO2 + H2O2 L'enzima è una flavoproteina (FAD) che richiede tiamina difosfato. Due equivalenti riducenti sono trasferiti dal carbanione del 2-idrossietil-tiamina-difosfato all'adiacente cofattore flavinico, generando 2-acetil-tiamina difosfato (AcThDP) e flavina ridotta. Il FADH2 è riossidato dall'O2 per generare H2O2, mentre il FAD ed il AcThDP sono riconvertiti dall'acetil fosfato e dalla tiamina pirofosfato. (it)
  • ピルビン酸オキシダーゼ(pyruvate oxidase)は、ピルビン酸代謝酵素の一つで、次の化学反応を触媒する酸化還元酵素である。 ピルビン酸 + リン酸 + O2 アセチルリン酸 + CO2 + H2O2 反応式の通り、この酵素の基質はピルビン酸とリン酸と酸素、生成物はと二酸化炭素と過酸化水素である。補因子としてFADとチアミンピロリン酸を用いる。 組織名はpyruvate:oxygen 2-oxidoreductase (phosphorylating)で、別名にpyruvic oxidase, phosphate-dependent pyruvate oxidaseがある。 (ja)
  • In enzymology, a pyruvate oxidase (EC 1.2.3.3) is an enzyme that catalyzes the chemical reaction pyruvate + phosphate + O2 acetyl phosphate + CO2 + H2O2 The 3 substrates of this enzyme are pyruvate, phosphate, and O2, whereas its 3 products are , CO2, and H2O2. (en)
rdfs:label
  • Pyruvate oxydase (fr)
  • Piruvato ossidasi (it)
  • ピルビン酸オキシダーゼ (ja)
  • Pyruvate oxidase (en)
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  • pyruvate oxidase (en)
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