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Preprotachykinins are precursor proteins that are modified into tachykinin peptides. Via alternative splicing and post-translational modifications, preprotachykinins produce multiple peptide neurotransmitters. There are two human preprotachykinins: 1. * preprotachykinin-1 (also PPT-1, PPT-I, or PPT-A), which produces substance P and neurokinin A (also called "substance K"), and the derived neuropeptide K and . 2. * (also PPT-2, PPT-II, or PPT-B), which produces neurokinin B.
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