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Plasminogen activators are serine proteases that catalyze the activation of plasmin via proteolytic cleavage of its zymogen form plasminogen. Plasmin is an important factor in fibrinolysis, the breakdown of fibrin polymers formed during blood clotting. There are two main plasminogen activators: urokinase (uPA) and tissue plasminogen activator (tPA). Tissue plasminogen activators are used to treat medical conditions related to blood clotting including embolic or thrombotic stroke, myocardial infarction, and pulmonary embolism.

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  • Plasminogen activators are serine proteases that catalyze the activation of plasmin via proteolytic cleavage of its zymogen form plasminogen. Plasmin is an important factor in fibrinolysis, the breakdown of fibrin polymers formed during blood clotting. There are two main plasminogen activators: urokinase (uPA) and tissue plasminogen activator (tPA). Tissue plasminogen activators are used to treat medical conditions related to blood clotting including embolic or thrombotic stroke, myocardial infarction, and pulmonary embolism. Plasminogen activators are inhibited by plasminogen activator inhibitor-1, plasminogen activator inhibitor-2, and protein C inhibitor. (en)
  • Um ativador de plasminogênio é uma serina protease que converte o plasminogênio em plasmina, promovendo assim a fibrinólise. (pt)
  • 纤维蛋白溶酶原激活物(英語:plasminogen activator,或译为纤溶蛋白酶原激活物,简称纤溶酶原激活物)是一种丝氨酸蛋白酶,它可以将纤溶蛋白酶原转化为纤溶蛋白酶,从而促进。种类有: * (tPA) * 尿纤溶酶原激活物 它受到和的抑制。 (zh)
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  • Um ativador de plasminogênio é uma serina protease que converte o plasminogênio em plasmina, promovendo assim a fibrinólise. (pt)
  • 纤维蛋白溶酶原激活物(英語:plasminogen activator,或译为纤溶蛋白酶原激活物,简称纤溶酶原激活物)是一种丝氨酸蛋白酶,它可以将纤溶蛋白酶原转化为纤溶蛋白酶,从而促进。种类有: * (tPA) * 尿纤溶酶原激活物 它受到和的抑制。 (zh)
  • Plasminogen activators are serine proteases that catalyze the activation of plasmin via proteolytic cleavage of its zymogen form plasminogen. Plasmin is an important factor in fibrinolysis, the breakdown of fibrin polymers formed during blood clotting. There are two main plasminogen activators: urokinase (uPA) and tissue plasminogen activator (tPA). Tissue plasminogen activators are used to treat medical conditions related to blood clotting including embolic or thrombotic stroke, myocardial infarction, and pulmonary embolism. (en)
rdfs:label
  • Plasminogen activator (en)
  • Ativador do plasminogênio (pt)
  • 纤维蛋白溶酶原激活物 (zh)
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