About: Pikromycin

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Pikromycin was studied by Brokmann and Hekel in 1951 and was the first antibiotic macrolide to be isolated.Pikromycin is synthesized through a type I polyketide synthase system in Streptomyces venezuelae, a species of Gram-positive bacterium in the genus Streptomyces.Pikromycin is derived from , a 14-membered ring macrolide.Along with the narbonolide backbone, pikromycin includes a desosamine sugar and a hydroxyl group. Although Pikromycin is not a clinically useful antibiotic, it can be used as a raw material to synthesize antibiotic ketolide compounds such as ertythromycins and new epothilones.

thumbnail
Property Value
dbo:abstract
  • Pikromycin was studied by Brokmann and Hekel in 1951 and was the first antibiotic macrolide to be isolated.Pikromycin is synthesized through a type I polyketide synthase system in Streptomyces venezuelae, a species of Gram-positive bacterium in the genus Streptomyces.Pikromycin is derived from , a 14-membered ring macrolide.Along with the narbonolide backbone, pikromycin includes a desosamine sugar and a hydroxyl group. Although Pikromycin is not a clinically useful antibiotic, it can be used as a raw material to synthesize antibiotic ketolide compounds such as ertythromycins and new epothilones. (en)
dbo:alternativeName
  • Picromycin (en)
dbo:iupacName
  • (3R,5R,6S,7S,9R,11E,13S,14R)-6-{[(2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-13-hydroxy-3,5,7,9,13-pentamethyl-1-oxacyclotetradec-11-ene-2,4,10-trione (en)
  • (3R,5R,6S,7S,9R,11E,13S,14R)-14-Ethyl-13-hydroxy-3,5,7,9,13-pentamethyl-6-[3,4,6-trideoxy-3-(dimethylamino)-β-(D)-xylo-hexopyranosyloxy]-1-oxacyclotetradec-11-ene-2,4,10-trione (en)
dbo:thumbnail
dbo:wikiPageID
  • 31924946 (xsd:integer)
dbo:wikiPageLength
  • 7477 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID
  • 1027277970 (xsd:integer)
dbo:wikiPageWikiLink
dbp:imagefile
  • Pikromycin.svg (en)
dbp:iupacname
  • -14 (xsd:integer)
dbp:othernames
  • Picromycin (en)
dbp:pin
  • -6 (xsd:integer)
dbp:verifiedfields
  • changed (en)
dbp:verifiedrevid
  • 450797983 (xsd:integer)
dbp:watchedfields
  • changed (en)
dbp:wikiPageUsesTemplate
dcterms:subject
gold:hypernym
rdf:type
rdfs:comment
  • Pikromycin was studied by Brokmann and Hekel in 1951 and was the first antibiotic macrolide to be isolated.Pikromycin is synthesized through a type I polyketide synthase system in Streptomyces venezuelae, a species of Gram-positive bacterium in the genus Streptomyces.Pikromycin is derived from , a 14-membered ring macrolide.Along with the narbonolide backbone, pikromycin includes a desosamine sugar and a hydroxyl group. Although Pikromycin is not a clinically useful antibiotic, it can be used as a raw material to synthesize antibiotic ketolide compounds such as ertythromycins and new epothilones. (en)
rdfs:label
  • Pikromycin (en)
owl:sameAs
prov:wasDerivedFrom
foaf:depiction
foaf:isPrimaryTopicOf
is dbo:wikiPageRedirects of
is dbo:wikiPageWikiLink of
is foaf:primaryTopic of
Powered by OpenLink Virtuoso    This material is Open Knowledge     W3C Semantic Web Technology     This material is Open Knowledge    Valid XHTML + RDFa
This content was extracted from Wikipedia and is licensed under the Creative Commons Attribution-ShareAlike 3.0 Unported License