About: Phenacemide

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Phenacemide (INN, BAN) (brand name Phenurone), also known as phenylacetylurea, is an anticonvulsant of the ureide (acetylurea) class. It is a congener and ring-opened analogue of phenytoin (a hydantoin), and is structurally related to the barbiturates and to other hydantoins. Phenacemide was introduced in 1949 for the treatment of epilepsy, but was eventually withdrawn due to toxicity.

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dbo:abstract
  • فيناسيميد (بالإنجليزية: Phenacemide)‏ هو دواء يُستعمل في علاج: * نوبة جزئية مركبة (ar)
  • Phenacemide (INN, BAN) (brand name Phenurone), also known as phenylacetylurea, is an anticonvulsant of the ureide (acetylurea) class. It is a congener and ring-opened analogue of phenytoin (a hydantoin), and is structurally related to the barbiturates and to other hydantoins. Phenacemide was introduced in 1949 for the treatment of epilepsy, but was eventually withdrawn due to toxicity. (en)
  • La fenacemide è un farmaco anticonvulsivante derivato dall'urea ed appartenente ad una categoria molto eterogenea di sostanze denominate ossazolidindioni. Sebbene il farmaco abbia una catena lineare caratterizzata da diversi gruppi di acetilurea, allo stato cristallino la molecole adotta una conformazione pseudociclica che la rende molto simile a quella della difenilidantoina e di altri composti eterociclici di tipo anticonvulsivante. (it)
dbo:alternativeName
  • Phenurone (en)
dbo:casNumber
  • 63-98-9
dbo:chEMBL
  • 918
dbo:drugbank
  • DB01121
dbo:fdaUniiCode
  • PAI7J52V09
dbo:kegg
  • D00504
dbo:pubchem
  • 4753
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  • N03 (en)
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  • AX07 (en)
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  • 9 (xsd:integer)
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  • 63 (xsd:integer)
dbp:chembl
  • 918 (xsd:integer)
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  • 4589 (xsd:integer)
dbp:drugbank
  • DB01121 (en)
dbp:eliminationHalfLife
  • -90000.0
dbp:h
  • 10 (xsd:integer)
dbp:iupacName
  • N-Carbamoyl-2-phenyl-acetamide (en)
dbp:iupharLigand
  • 7265 (xsd:integer)
dbp:kegg
  • D00504 (en)
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  • 2 (xsd:integer)
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  • 2 (xsd:integer)
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  • 4753 (xsd:integer)
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  • O=CCc1ccccc1 (en)
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  • 1 (xsd:integer)
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  • XPFRXWCVYUEORT-UHFFFAOYSA-N (en)
dbp:tradename
  • Phenurone (en)
dbp:unii
  • PAI7J52V09 (en)
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  • 464199698 (xsd:integer)
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  • changed (en)
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  • 175 (xsd:integer)
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  • فيناسيميد (بالإنجليزية: Phenacemide)‏ هو دواء يُستعمل في علاج: * نوبة جزئية مركبة (ar)
  • Phenacemide (INN, BAN) (brand name Phenurone), also known as phenylacetylurea, is an anticonvulsant of the ureide (acetylurea) class. It is a congener and ring-opened analogue of phenytoin (a hydantoin), and is structurally related to the barbiturates and to other hydantoins. Phenacemide was introduced in 1949 for the treatment of epilepsy, but was eventually withdrawn due to toxicity. (en)
  • La fenacemide è un farmaco anticonvulsivante derivato dall'urea ed appartenente ad una categoria molto eterogenea di sostanze denominate ossazolidindioni. Sebbene il farmaco abbia una catena lineare caratterizzata da diversi gruppi di acetilurea, allo stato cristallino la molecole adotta una conformazione pseudociclica che la rende molto simile a quella della difenilidantoina e di altri composti eterociclici di tipo anticonvulsivante. (it)
rdfs:label
  • فيناسيميد (ar)
  • Fenacemide (it)
  • Phenacemide (en)
  • 苯乙酰脲 (zh)
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