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- Le matériel péricentriolaire est le nuage de matériel amorphe qui entoure une paire de centrioles (centre organisateur des microtubules). Il est composé de protéines fibrogranulaires.
* Portail de la biologie cellulaire et moléculaire (fr)
- Pericentriolar material (PCM, sometimes also called pericent matrix) is a highly structured, dense mass of protein which makes up the part of the animal centrosome that surrounds the two centrioles. The PCM contains proteins responsible for microtubule nucleation and including γ-tubulin, pericentrin and ninein. Although the PCM appears amorphous by electron microscopy, super-resolution microscopy finds that it is highly organized. The PCM have 9-fold symmetry that mimics the symmetry of the centriole. Some PCM proteins are organized such that one end of the protein is found near the centriole and the other end is farther away from the centriole.The PCM size is dynamic during the cell cycle. After cell division, the PCM size is reduced in a process named centrosome reduction. During the G2 phase of the cell cycle, the PCM grows in size in a process named centrosome maturation. According to the Gene Ontology, the following human proteins are associated with the PCM [1]:
* BBS4, Bardet-Biedl syndrome 4 protein
* Lck, Proto-oncogene tyrosine-protein kinase LCK
* PCM1, Pericentriolar material 1 protein
* TNKS, Tankyrase-1
* TNKS2, Tankyrase-2
* TUBE1, Tubulin epsilon chain
* PCNT, pericentrin, a matrix scaffold protein
* CDK5RAP2, cyclin dependant kinase receptor associated protein 2, binds gTubRCs that nucleate microtubules
* NEDD1, binds gTubRCs that stabilise microtubules
* Gamma Tubulin, nucleates microtubules (en)
- 中心体マトリックス (ちゅうしんたいまとりっくす、Pericentriolar material(PCM)）は、円筒状の構造である中心小体とともに中心体を構成する要素の一つ。中心小体の外側を取り囲む、アモルファス状の構造体であると考えられている。中心体マトリクスともいう。 (ja)
- O material pericentriolar é uma massa amorfa de proteínas que constitui a parte do centrossoma animal que rodeia os dois centríolos. Este material é responsável pela e pela incluindo γ-tubulina, e . De acordo com a ontologia genética, as seguintes proteínas humanas estão associadas a este material [1]:
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- Le matériel péricentriolaire est le nuage de matériel amorphe qui entoure une paire de centrioles (centre organisateur des microtubules). Il est composé de protéines fibrogranulaires.
* Portail de la biologie cellulaire et moléculaire (fr)
- 中心体マトリックス (ちゅうしんたいまとりっくす、Pericentriolar material(PCM)）は、円筒状の構造である中心小体とともに中心体を構成する要素の一つ。中心小体の外側を取り囲む、アモルファス状の構造体であると考えられている。中心体マトリクスともいう。 (ja)
- O material pericentriolar é uma massa amorfa de proteínas que constitui a parte do centrossoma animal que rodeia os dois centríolos. Este material é responsável pela e pela incluindo γ-tubulina, e . De acordo com a ontologia genética, as seguintes proteínas humanas estão associadas a este material [1]:
*
*
*
*
*
* (pt)
- Pericentriolar material (PCM, sometimes also called pericent matrix) is a highly structured, dense mass of protein which makes up the part of the animal centrosome that surrounds the two centrioles. The PCM contains proteins responsible for microtubule nucleation and including γ-tubulin, pericentrin and ninein. According to the Gene Ontology, the following human proteins are associated with the PCM [1]: (en)
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- Matériel péricentriolaire (fr)
- 中心体マトリックス (ja)
- Pericentriolar material (en)
- Material pericentriolar (pt)
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