The Parry Sound Colonization Railway Company (PSCR) was a Canadian railway that operated in Ontario. It originally intended to connect the town of Parry Sound to the Northern and Pacific Junction Railway but ran out of funds shortly after starting construction. The line was purchased by John Rudolphus Booth in 1892 to form the western end of his Ottawa, Arnprior and Parry Sound Railway. Failing to come to an agreement on the location of an associated port, the line ultimately bypassed the town completely, running to Depot Harbour, a company town.