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- Palmitoyl-CoA hydrolase (EC 3.1.2.2) is an enzyme in the family of hydrolases that specifically acts on thioester bonds. It catalyzes the hydrolysis of long chain fatty acyl thioesters of acyl carrier protein or coenzyme A to form free fatty acid and the corresponding thiol: palmitoyl-CoA + H2O = CoA + palmitate It has a strict specificity for thioesters with a chain link greater than C10. These enzymes are localized in almost all cellular compartments, such as endoplasmic reticulum, cytosol, mitochondria, and peroxisomes. They are highly regulated by peroxisome proliferator activated receptors, which led to their involvement in lipid metabolism. The enzyme is up-regulated during times of increased fatty acid oxidation, which suggests that this enzyme has a potential role the peroxisomal beta-oxidation. The systematic name is palmitoyl-CoA hydrolase. Other names in common use include long-chain fatty-acyl-CoA hydrolase, palmitoyl coenzyme A hydrolase, palmitoyl thioesterase, palmitoyl coenzyme A hydrolase, palmitoyl-CoA deacylase, palmityl thioesterase, palmityl-CoA deacylase, fatty acyl thioesterase I, and palmityl thioesterase I. (en)
- パルミトイルCoAヒドロラーゼ(Palmitoyl-CoA hydrolase、EC 3.1.2.2)は、以下の化学反応を触媒する酵素である。 パルミトイルCoA+水補酵素A+パルミチン酸 従って、この酵素の2つの基質はと水、2つの生成物は補酵素Aとパルミチン酸である。 この酵素は、加水分解酵素に分類され、特にチオエステル結合に作用する。系統名は、パルミトイルCoAヒドロラーゼである。この酵素は、パルミチン酸の代謝に関与している。 (ja)
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- 6893 (xsd:nonNegativeInteger)
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- palmitoyl-CoA hydrolase (en)
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- パルミトイルCoAヒドロラーゼ(Palmitoyl-CoA hydrolase、EC 3.1.2.2)は、以下の化学反応を触媒する酵素である。 パルミトイルCoA+水補酵素A+パルミチン酸 従って、この酵素の2つの基質はと水、2つの生成物は補酵素Aとパルミチン酸である。 この酵素は、加水分解酵素に分類され、特にチオエステル結合に作用する。系統名は、パルミトイルCoAヒドロラーゼである。この酵素は、パルミチン酸の代謝に関与している。 (ja)
- Palmitoyl-CoA hydrolase (EC 3.1.2.2) is an enzyme in the family of hydrolases that specifically acts on thioester bonds. It catalyzes the hydrolysis of long chain fatty acyl thioesters of acyl carrier protein or coenzyme A to form free fatty acid and the corresponding thiol: palmitoyl-CoA + H2O = CoA + palmitate It has a strict specificity for thioesters with a chain link greater than C10. (en)
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- パルミトイルCoAヒドロラーゼ (ja)
- Palmitoyl-CoA hydrolase (en)
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- palmitoyl-CoA hydrolase (en)
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