About: PRE-084

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

PRE-084 is a sigma receptor agonist, selective for the σ1 subtype. It has nootropic and antidepressant actions in animal studies, as well as antitussive and reinforcing effects. PRE-084 increases the expression of GDNF.

Property	Value
dbo:abstract	PRE-084 is a sigma receptor agonist, selective for the σ1 subtype. It has nootropic and antidepressant actions in animal studies, as well as antitussive and reinforcing effects. PRE-084 increases the expression of GDNF. (en)
dbo:casNumber	138847-85-5
dbo:pubchem	126402
dbo:thumbnail	wiki-commons:Special:FilePath/PRE-084_SVG_file.svg?width=300
dbo:wikiPageID	27984902 (xsd:integer)
dbo:wikiPageLength	4649 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID	1119898008 (xsd:integer)
dbo:wikiPageWikiLink	dbr:File:PRE-084_synthesis.svg dbr:Benzyl_cyanide dbr:GDNF dbc:Carboxylate_esters dbr:Thionyl_chloride dbr:Antidepressant dbr:Agonist dbc:Sigma_agonists dbr:Nootropic dbc:Morpholines dbr:Antitussive dbr:Sigma_receptor dbr:Sigma-1_receptor
dbp:atcPrefix	none (en)
dbp:c	19 (xsd:integer)
dbp:casNumber	138847 (xsd:integer)
dbp:chemspiderid	112335 (xsd:integer)
dbp:h	27 (xsd:integer)
dbp:iupacName	2 (xsd:integer)
dbp:iupharLigand	6678 (xsd:integer)
dbp:n	1 (xsd:integer)
dbp:o	3 (xsd:integer)
dbp:pubchem	126402 (xsd:integer)
dbp:smiles	c1ccccc1C2COCCN3CCOCC3 (en)
dbp:stdinchi	1 (xsd:integer)
dbp:stdinchikey	RQHKZUBCUZVZEF-UHFFFAOYSA-N (en)
dbp:verifiedfields	changed (en)
dbp:verifiedrevid	451562202 (xsd:integer)
dbp:width	200 (xsd:integer)
dbp:wikiPageUsesTemplate	dbt:Drugbox dbt:Pharm-stub dbt:Reflist dbt:Short_description dbt:Cascite dbt:Chemspidercite dbt:Stdinchicite dbt:Sigma_receptor_modulators
dcterms:subject	dbc:Carboxylate_esters dbc:Sigma_agonists dbc:Morpholines
gold:hypernym	dbr:Agonist
rdf:type	owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 yago:WikicatCarboxylateEsters yago:Abstraction100002137 yago:Chemical114806838 yago:Compound114818238 yago:Ester114850483 yago:Material114580897 yago:Matter100020827 yago:OrganicCompound114727670 yago:Part113809207 yago:PhysicalEntity100001930 yago:Relation100031921 dbo:Drug yago:Substance100019613
rdfs:comment	PRE-084 is a sigma receptor agonist, selective for the σ1 subtype. It has nootropic and antidepressant actions in animal studies, as well as antitussive and reinforcing effects. PRE-084 increases the expression of GDNF. (en)
rdfs:label	PRE-084 (en)
owl:sameAs	freebase:PRE-084 yago-res:PRE-084 wikidata:PRE-084 dbpedia-sh:PRE-084 dbpedia-sr:PRE-084 https://global.dbpedia.org/id/2VUtb
prov:wasDerivedFrom	wikipedia-en:PRE-084?oldid=1119898008&ns=0
foaf:depiction	wiki-commons:Special:FilePath/PRE-084_SVG_file.svg wiki-commons:Special:FilePath/PRE-084_synthesis.svg
foaf:isPrimaryTopicOf	wikipedia-en:PRE-084
is dbo:wikiPageWikiLink of	dbr:Arylcyclohexylamine dbr:C19H27NO3 dbr:Methylphenylpiracetam dbr:Sigma_receptor dbr:Sigma-1_receptor
is foaf:primaryTopic of	wikipedia-en:PRE-084