About: Oxotremorine

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Oxotremorine is a drug that acts as a selective muscarinic acetylcholine receptor agonist. Oxotremorine produces ataxia, tremor and spasticity, similar to those symptoms seen in Parkinsonism, and has thus become a research tool in experimental studies aimed at determining more effective anti-Parkinsonian drugs. Oxotremorine also produces antipsychotic effects.

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dbo:abstract
  • La oxotremorina es un medicamento alcaloide sintético que actúa como agonista no selectivo de los receptores muscarínicos, como los receptores tipo M1 y M3, por lo que es una droga parasimpaticomimética. (es)
  • Oxotremorine is a drug that acts as a selective muscarinic acetylcholine receptor agonist. Oxotremorine produces ataxia, tremor and spasticity, similar to those symptoms seen in Parkinsonism, and has thus become a research tool in experimental studies aimed at determining more effective anti-Parkinsonian drugs. Oxotremorine also produces antipsychotic effects. (en)
  • L'oxotremorina è un alcaloide sintetico ed un in grado di legarsi al recettore dell'acetilcolina. Non è però un agonista selettivo. Produce atassia, tremori e spasticità simil-parkinsoniani. Non ha utilizzi medico-farmacologici, ma viene utilizzata come molecola per lo studio di altri farmaci ad attività antiparkinsoniana. (it)
dbo:casNumber
  • 70-22-4
dbo:chEMBL
  • 7634
dbo:fdaUniiCode
  • 5RY0UWH1JL
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  • 3211 (xsd:nonNegativeInteger)
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  • none (en)
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  • 12 (xsd:integer)
dbp:casNumber
  • 70 (xsd:integer)
dbp:chembl
  • 7634 (xsd:integer)
dbp:chemspiderid
  • 4469 (xsd:integer)
dbp:h
  • 18 (xsd:integer)
dbp:iupacName
  • 1 (xsd:integer)
dbp:iupharLigand
  • 302 (xsd:integer)
dbp:legalUsComment
  • Experimental/not yet approved (en)
dbp:molecularWeight
  • 206.280000 (xsd:double)
dbp:n
  • 2 (xsd:integer)
dbp:o
  • 1 (xsd:integer)
dbp:pregnancyCategory
  • C (en)
dbp:routesOfAdministration
  • Oral, intravenous (en)
dbp:smiles
  • C1CCNCC#CCN2CCCC2=O (en)
dbp:stdinchi
  • InChI=1S/C12H18N2O/c15-12-6-5-11-1410-4-3-9-13-7-1-2-8-13/h1-2,5-11H2 (en)
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  • RSDOPYMFZBJHRL-UHFFFAOYSA-N (en)
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  • changed (en)
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  • 383299199 (xsd:integer)
dbp:watchedfields
  • changed (en)
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  • 200 (xsd:integer)
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gold:hypernym
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rdfs:comment
  • La oxotremorina es un medicamento alcaloide sintético que actúa como agonista no selectivo de los receptores muscarínicos, como los receptores tipo M1 y M3, por lo que es una droga parasimpaticomimética. (es)
  • Oxotremorine is a drug that acts as a selective muscarinic acetylcholine receptor agonist. Oxotremorine produces ataxia, tremor and spasticity, similar to those symptoms seen in Parkinsonism, and has thus become a research tool in experimental studies aimed at determining more effective anti-Parkinsonian drugs. Oxotremorine also produces antipsychotic effects. (en)
  • L'oxotremorina è un alcaloide sintetico ed un in grado di legarsi al recettore dell'acetilcolina. Non è però un agonista selettivo. Produce atassia, tremori e spasticità simil-parkinsoniani. Non ha utilizzi medico-farmacologici, ma viene utilizzata come molecola per lo studio di altri farmaci ad attività antiparkinsoniana. (it)
rdfs:label
  • Oxotremorina (es)
  • Oxotremorina (it)
  • Oxotremorine (en)
owl:sameAs
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foaf:depiction
foaf:isPrimaryTopicOf
is dbo:wikiPageWikiLink of
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