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- أولسالازين Olsalazine هو أولسالازين الصوديوم. (ar)
- Olsalazine is an anti-inflammatory medication used in the treatment of ulcerative colitis. It is sold under the brand name Dipentum. Olsalazine itself is a pro-drug of mesalazine (5-aminosalicyclic acid or 5-ASA) and is not absorbed in the small intestine. Instead it continues through to the colon where it is cleaved into two molecules of 5-ASA by azoreductases produced by colonic bacteria. Olsalazine thus exerts its anti-inflammatory effect by its colonic breakdown into 5-ASA which inhibits cyclooxygenase and lipoxygenase thereby reducing prostaglandin and leukotriene production. (en)
- L'olsalazina è un farmaco antinfiammatorio non steroideo appartenente alla classe dei salicilati e usato nel trattamento delle malattie infiammatorie croniche intestinali come la rettocolite ulcerosa. Come per la balsalazide si ritiene che sia un profarmaco la cui forma attiva è costituita dalla mesalazina ovvero l'acido 5-amminosalicilico (5-ASA) cui viene trasformata selettivamente nel colon, essendo pertanto utile nel trattamento della colite ulcerosa. (it)
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- أولسالازين Olsalazine هو أولسالازين الصوديوم. (ar)
- Olsalazine is an anti-inflammatory medication used in the treatment of ulcerative colitis. It is sold under the brand name Dipentum. Olsalazine itself is a pro-drug of mesalazine (5-aminosalicyclic acid or 5-ASA) and is not absorbed in the small intestine. Instead it continues through to the colon where it is cleaved into two molecules of 5-ASA by azoreductases produced by colonic bacteria. Olsalazine thus exerts its anti-inflammatory effect by its colonic breakdown into 5-ASA which inhibits cyclooxygenase and lipoxygenase thereby reducing prostaglandin and leukotriene production. (en)
- L'olsalazina è un farmaco antinfiammatorio non steroideo appartenente alla classe dei salicilati e usato nel trattamento delle malattie infiammatorie croniche intestinali come la rettocolite ulcerosa. Come per la balsalazide si ritiene che sia un profarmaco la cui forma attiva è costituita dalla mesalazina ovvero l'acido 5-amminosalicilico (5-ASA) cui viene trasformata selettivamente nel colon, essendo pertanto utile nel trattamento della colite ulcerosa. (it)
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- أولسالازين (ar)
- Olsalazina (it)
- Olsalazine (en)
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