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- Octamer transcription factors are a family of transcription factors which binds to the "ATTTGCAT" DNA sequence. Their DNA-binding domain is a POU domain. There are eight Octamer proteins in humans (Oct1–11), which have been renamed according to the different classes of POU domain. Octamer-3/4, also known as POU5F1, is one of the Yamanaka factors, which are critical for the maintenance and self-renewal of embryonic stem cells. On the other hand, Oct-1 and Oct-2 are widely expressed in adult tissues. Oct-7, 8 and 9, also known as "brain factors", are predominantly expressed in the central nervous system during embryonic development. Oct-6 expression is confined to embryonic stem cells and the developing nervous system and skin, while Oct-11 is also involved in skin differentiation. (en)
- Um fator de transcrição octâmero é um fator de transcrição que se liga à sequência "ATTTGCAT". Exemplos incluem:
* - POU2F1
* - POU2F2
* – POU5F1
* – POU3F1
* – POU3F2
* - POU3F3
* – POU3F4
* – POU3F4 (pt)
- 八聚体转录因子（英語：octamer transcription factor）是一类能结合到序列"ATTTGCAT"上的转录因子。 例子包括：
* - POU2F1
* - POU2F2
* Oct-3/4 – POU5F1
* – POU3F1
* – POU3F2
* Oct-8 - POU3F3
* – POU3F4
* – POU3F4 (zh)
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- 2412 (xsd:nonNegativeInteger)
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| rdfs:comment
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- Octamer transcription factors are a family of transcription factors which binds to the "ATTTGCAT" DNA sequence. Their DNA-binding domain is a POU domain. There are eight Octamer proteins in humans (Oct1–11), which have been renamed according to the different classes of POU domain. Octamer-3/4, also known as POU5F1, is one of the Yamanaka factors, which are critical for the maintenance and self-renewal of embryonic stem cells. On the other hand, Oct-1 and Oct-2 are widely expressed in adult tissues. Oct-7, 8 and 9, also known as "brain factors", are predominantly expressed in the central nervous system during embryonic development. Oct-6 expression is confined to embryonic stem cells and the developing nervous system and skin, while Oct-11 is also involved in skin differentiation. (en)
- Um fator de transcrição octâmero é um fator de transcrição que se liga à sequência "ATTTGCAT". Exemplos incluem:
* - POU2F1
* - POU2F2
* – POU5F1
* – POU3F1
* – POU3F2
* - POU3F3
* – POU3F4
* – POU3F4 (pt)
- 八聚体转录因子（英語：octamer transcription factor）是一类能结合到序列"ATTTGCAT"上的转录因子。 例子包括：
* - POU2F1
* - POU2F2
* Oct-3/4 – POU5F1
* – POU3F1
* – POU3F2
* Oct-8 - POU3F3
* – POU3F4
* – POU3F4 (zh)
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| rdfs:label
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- Octamer transcription factor (en)
- Fator de transcrição de octâmero (pt)
- 八聚体转录因子 (zh)
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