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- Les protéines non-histones (PNH) sont des protéines chargées positivement (charge plus faible que celle des histones) situées dans le noyau cellulaire mais non liées à l'ADN comme les histones. Font partie des PNH :
* cohésine ;
* condensine ;
* PRC2 ;
* la famille des HP1 ;
* certaines kinases nucléaires (MAP kinases) ;
* certaines transférases (acétyltransférases, méthyltransférases) ;
* certaines ligases (E1-,E2- et E3-ligases, NEDD8, etc.). (fr)
- In chromatin, those proteins which remain after the histones have been removed, are classified as non-histone proteins. The non-histone proteins, are a large group of heterogeneous proteins that play a role in organization and compaction of the chromosome into higher order structures. They play vital roles in regulating processes like nucleosome remodeling, DNA replication, RNA synthesis and processing, nuclear transport, steroid hormone action and interphase/mitosis transition.Scaffold proteins, DNA polymerase, Heterochromatin Protein 1 and Polycomb are common non-histone proteins. This classification group also includes numerous other structural, regulatory, and motor proteins. Non-histone protein are acidic. (en)
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- Les protéines non-histones (PNH) sont des protéines chargées positivement (charge plus faible que celle des histones) situées dans le noyau cellulaire mais non liées à l'ADN comme les histones. Font partie des PNH :
* cohésine ;
* condensine ;
* PRC2 ;
* la famille des HP1 ;
* certaines kinases nucléaires (MAP kinases) ;
* certaines transférases (acétyltransférases, méthyltransférases) ;
* certaines ligases (E1-,E2- et E3-ligases, NEDD8, etc.). (fr)
- In chromatin, those proteins which remain after the histones have been removed, are classified as non-histone proteins. The non-histone proteins, are a large group of heterogeneous proteins that play a role in organization and compaction of the chromosome into higher order structures. They play vital roles in regulating processes like nucleosome remodeling, DNA replication, RNA synthesis and processing, nuclear transport, steroid hormone action and interphase/mitosis transition.Scaffold proteins, DNA polymerase, Heterochromatin Protein 1 and Polycomb are common non-histone proteins. This classification group also includes numerous other structural, regulatory, and motor proteins. Non-histone protein are acidic. (en)
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- Protéine non-histone (fr)
- Non-histone protein (en)
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