About: Nargenicin

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Nargenicin (CP-47,444, CS-682) is a 28 carbon macrolide with a fused tricyclic core that has in addition a unique ether bridge. The polyketide antibiotic was isolated from Nocardia argentinensis. Nargenicin is effective towards gram-positive bacteria and been shown to have strong antibacterial activity against Staphylococcus aureus, including strains that are resistant to methicillin. It has also been shown to induce cell differentiation and inhibit cell proliferation in a human myeloid leukemia cell line.

Property Value
dbo:abstract
  • Nargenicin (CP-47,444, CS-682) is a 28 carbon macrolide with a fused tricyclic core that has in addition a unique ether bridge. The polyketide antibiotic was isolated from Nocardia argentinensis. Nargenicin is effective towards gram-positive bacteria and been shown to have strong antibacterial activity against Staphylococcus aureus, including strains that are resistant to methicillin. It has also been shown to induce cell differentiation and inhibit cell proliferation in a human myeloid leukemia cell line. (en)
  • 나르제니신 (Nargenicin)은 28탄소로 이루어진 매크로라이드계 항생제이다. 나르제니신은 그람 양성균에 탁월한 효과를 보이며 메티실린에 저항성이 있는 포도상구균에 강력한 항생제 역할을 해왔다. 또한 세포분화를 유도하는 역할도 있으며 종양 질환에 사용되어 지기도 한다. (ko)
dbo:casNumber
  • 70695-02-2
dbo:fdaUniiCode
  • XP2QP458K4
dbo:pubchem
  • 6436286
dbo:thumbnail
dbo:wikiPageID
  • 23091305 (xsd:integer)
dbo:wikiPageLength
  • 5368 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID
  • 1086174799 (xsd:integer)
dbo:wikiPageWikiLink
dbp:atcPrefix
  • none (en)
dbp:c
  • 28 (xsd:integer)
dbp:casNumber
  • 70695 (xsd:integer)
dbp:chemspiderid
  • 4885360 (xsd:integer)
dbp:excretion
  • ~ (en)
dbp:h
  • 37 (xsd:integer)
dbp:jmol
  • none (en)
dbp:n
  • 1 (xsd:integer)
dbp:o
  • 8 (xsd:integer)
dbp:pubchem
  • 6436286 (xsd:integer)
dbp:smiles
  • O=C2O[C@H][C@@H]C (en)
dbp:stdinchi
  • 1 (xsd:integer)
dbp:stdinchikey
  • YEUSSARNQQYBKH-KFIBIINQSA-N (en)
dbp:unii
  • XP2QP458K4 (en)
dbp:verifiedrevid
  • 421771397 (xsd:integer)
dbp:width
  • 250 (xsd:integer)
dbp:wikiPageUsesTemplate
dcterms:subject
gold:hypernym
rdf:type
rdfs:comment
  • Nargenicin (CP-47,444, CS-682) is a 28 carbon macrolide with a fused tricyclic core that has in addition a unique ether bridge. The polyketide antibiotic was isolated from Nocardia argentinensis. Nargenicin is effective towards gram-positive bacteria and been shown to have strong antibacterial activity against Staphylococcus aureus, including strains that are resistant to methicillin. It has also been shown to induce cell differentiation and inhibit cell proliferation in a human myeloid leukemia cell line. (en)
  • 나르제니신 (Nargenicin)은 28탄소로 이루어진 매크로라이드계 항생제이다. 나르제니신은 그람 양성균에 탁월한 효과를 보이며 메티실린에 저항성이 있는 포도상구균에 강력한 항생제 역할을 해왔다. 또한 세포분화를 유도하는 역할도 있으며 종양 질환에 사용되어 지기도 한다. (ko)
rdfs:label
  • 나르제니신 (ko)
  • Nargenicin (en)
owl:sameAs
prov:wasDerivedFrom
foaf:depiction
foaf:isPrimaryTopicOf
is dbo:wikiPageWikiLink of
is foaf:primaryTopic of
Powered by OpenLink Virtuoso    This material is Open Knowledge     W3C Semantic Web Technology     This material is Open Knowledge    Valid XHTML + RDFa
This content was extracted from Wikipedia and is licensed under the Creative Commons Attribution-ShareAlike 3.0 Unported License