About: Naltriben

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Naltriben is a potent and selective antagonist for the delta opioid receptor, which is used in scientific research. It has similar effects to the more widely used δ antagonist naltrindole, but with different binding affinity for the δ1 and δ2 subtypes, which makes it useful for distinguishing the subtype selectivity of drugs acting at the δ receptors. It also acts as a κ-opioid agonist at high doses.

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dbo:abstract
  • Naltriben is a potent and selective antagonist for the delta opioid receptor, which is used in scientific research. It has similar effects to the more widely used δ antagonist naltrindole, but with different binding affinity for the δ1 and δ2 subtypes, which makes it useful for distinguishing the subtype selectivity of drugs acting at the δ receptors. It also acts as a κ-opioid agonist at high doses. (en)
dbo:casNumber
  • 111555-58-9
dbo:chEMBL
  • 100940
dbo:fdaUniiCode
  • RXG719F189
dbo:pubchem
  • 5486827
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  • Skeletal formula (en)
  • Ball-and-stick model of naltriben (en)
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  • 111555 (xsd:integer)
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  • 100940 (xsd:integer)
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  • 25 (xsd:integer)
dbp:image
  • Naltriben molecule ball.png (en)
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  • ZHVWWEYETMPAMX-IFKAHUTRSA-N (en)
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  • RXG719F189 (en)
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  • Naltriben is a potent and selective antagonist for the delta opioid receptor, which is used in scientific research. It has similar effects to the more widely used δ antagonist naltrindole, but with different binding affinity for the δ1 and δ2 subtypes, which makes it useful for distinguishing the subtype selectivity of drugs acting at the δ receptors. It also acts as a κ-opioid agonist at high doses. (en)
rdfs:label
  • Naltriben (en)
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