About: Nalmexone

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Nalmexone (INN) (code names EN-1620A, UM-592), or nalmexone hydrochloride (USAN), is a semisynthetic, opioid partial agonist or mixed agonist-antagonist with both analgesic and narcotic antagonist properties that was never marketed. In clinical studies it was found to have comparable analgesic efficacy to morphine, though with several-fold reduced potency. In addition, nalmexone's side effects, the most common of which were sleepiness and sweating, were reported to be similar to those of morphine, albeit with a noticeably higher degree of incidence.

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dbo:abstract
  • نالمكسون (بالإنجليزية: Nalmexone)‏ هو مسكّن ألم قوي من فئة الأفيونيات. يعمل نالمكسون بشكل مباشر على الجهاز العصبي المركزي لتقليل الشعور بالألم. يمكن استخدامه لكل من الألم الحاد والألم المزمن. (ar)
  • Nalmexone (INN) (code names EN-1620A, UM-592), or nalmexone hydrochloride (USAN), is a semisynthetic, opioid partial agonist or mixed agonist-antagonist with both analgesic and narcotic antagonist properties that was never marketed. In clinical studies it was found to have comparable analgesic efficacy to morphine, though with several-fold reduced potency. In addition, nalmexone's side effects, the most common of which were sleepiness and sweating, were reported to be similar to those of morphine, albeit with a noticeably higher degree of incidence. (en)
dbo:casNumber
  • (HCl)
  • 16676-26-9
dbo:fdaUniiCode
  • AIB278UKIG
dbo:pubchem
  • 5360516
dbo:thumbnail
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  • None (en)
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  • 21 (xsd:integer)
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  • 16676 (xsd:integer)
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  • O=C4[C@@H]5Oc1c2cC[C@H]3NC\C=CC (en)
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  • OHKCLOQPSLQCQR-MBPVOVBZSA-N (en)
dbp:unii
  • AIB278UKIG (en)
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rdfs:comment
  • نالمكسون (بالإنجليزية: Nalmexone)‏ هو مسكّن ألم قوي من فئة الأفيونيات. يعمل نالمكسون بشكل مباشر على الجهاز العصبي المركزي لتقليل الشعور بالألم. يمكن استخدامه لكل من الألم الحاد والألم المزمن. (ar)
  • Nalmexone (INN) (code names EN-1620A, UM-592), or nalmexone hydrochloride (USAN), is a semisynthetic, opioid partial agonist or mixed agonist-antagonist with both analgesic and narcotic antagonist properties that was never marketed. In clinical studies it was found to have comparable analgesic efficacy to morphine, though with several-fold reduced potency. In addition, nalmexone's side effects, the most common of which were sleepiness and sweating, were reported to be similar to those of morphine, albeit with a noticeably higher degree of incidence. (en)
rdfs:label
  • نالمكسون (ar)
  • Nalmexone (en)
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