About: NV-5440

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

NV-5440 is a drug which acts as both a non-specific inhibitor of the glucose transporters and also a selective inhibitor of mTORC1, with no significant action at the related mTORC2 subtype. Compounds of this type have potential application in the treatment of cancer, and it is also used for research into the links between calorie restriction and longevity.

Property	Value
dbo:abstract	NV-5440 is a drug which acts as both a non-specific inhibitor of the glucose transporters and also a selective inhibitor of mTORC1, with no significant action at the related mTORC2 subtype. Compounds of this type have potential application in the treatment of cancer, and it is also used for research into the links between calorie restriction and longevity. (en)
dbo:casNumber	2226614-88-4
dbo:pubchem	134500648
dbo:thumbnail	wiki-commons:Special:FilePath/NV-5440_structure.png?width=300
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dbo:wikiPageLength	2413 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID	1073190365 (xsd:integer)
dbo:wikiPageWikiLink	dbr:Cancer dbr:MTORC1 dbr:MTORC2 dbr:Calorie_restriction dbr:Glucose_transporter dbc:Enzyme_inhibitors dbr:Longevity
dbp:c	31 (xsd:integer)
dbp:casNumber	2226614 (xsd:integer)
dbp:chemspiderid	98644474 (xsd:integer)
dbp:h	36 (xsd:integer)
dbp:iupacName	2 (xsd:integer)
dbp:n	6 (xsd:integer)
dbp:o	3 (xsd:integer)
dbp:pubchem	134500648 (xsd:integer)
dbp:s	1 (xsd:integer)
dbp:smiles	CC1=CCC (en)
dbp:stdinchi	1 (xsd:integer)
dbp:stdinchikey	BREWSTIKWAQLCH-UHFFFAOYSA-N (en)
dbp:wikiPageUsesTemplate	dbt:Drugbox dbt:Pharm-stub dbt:Reflist
dcterms:subject	dbc:Enzyme_inhibitors
rdf:type	owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 dbo:Drug
rdfs:comment	NV-5440 is a drug which acts as both a non-specific inhibitor of the glucose transporters and also a selective inhibitor of mTORC1, with no significant action at the related mTORC2 subtype. Compounds of this type have potential application in the treatment of cancer, and it is also used for research into the links between calorie restriction and longevity. (en)
rdfs:label	NV-5440 (en)
owl:sameAs	wikidata:NV-5440 https://global.dbpedia.org/id/FcEuY
prov:wasDerivedFrom	wikipedia-en:NV-5440?oldid=1073190365&ns=0
foaf:depiction	wiki-commons:Special:FilePath/NV-5440_structure.png
foaf:isPrimaryTopicOf	wikipedia-en:NV-5440
is dbo:wikiPageWikiLink of	dbr:MTORC1 dbr:List_of_signaling_peptide/protein_receptor_modulators
is foaf:primaryTopic of	wikipedia-en:NV-5440