About: Mir-129 microRNA precursor family

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The miR-129 microRNA precursor is a small non-coding RNA molecule that regulates gene expression. This microRNA was first experimentally characterised in mouse and homologues have since been discovered in several other species, such as humans, rats and zebrafish. The mature sequence is excised by the Dicer enzyme from the 5' arm of the hairpin. It was elucidated by Calin et al. that miR-129-1 is located in a fragile site region of the human genome near a specific site, FRA7H in chromosome 7q32, which is a site commonly deleted in many cancers. miR-129-2 is located in 11p11.2.

Property	Value
dbo:abstract	The miR-129 microRNA precursor is a small non-coding RNA molecule that regulates gene expression. This microRNA was first experimentally characterised in mouse and homologues have since been discovered in several other species, such as humans, rats and zebrafish. The mature sequence is excised by the Dicer enzyme from the 5' arm of the hairpin. It was elucidated by Calin et al. that miR-129-1 is located in a fragile site region of the human genome near a specific site, FRA7H in chromosome 7q32, which is a site commonly deleted in many cancers. miR-129-2 is located in 11p11.2. (en)
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dbo:wikiPageExternalLink	http://mirdb.org/cgi-bin/search.cgi%3FsearchType=miRNA&searchBox=hsa-miR-129-3p&full=1 http://mirdb.org/cgi-bin/search.cgi%3FsearchType=miRNA&searchBox=hsa-miR-129-5p&full=1 https://archive.today/20121223054724/http:/microrna.sanger.ac.uk/cgi-bin/sequences/mirna_summary.pl%3Ffam=MIPF0000073 https://web.archive.org/web/20101015061512/http:/www.ebi.ac.uk/gxa/gene/MIMAT0000242 https://www.ncbi.nlm.nih.gov/gene/406917 https://www.ncbi.nlm.nih.gov/gene/406918 https://semanticscholar.org/paper/06f8bc946e1d375bc780069f4ab5e8fcbf400783
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dbo:wikiPageWikiLink	dbr:MicroRNA dbr:CAMTA1 dbc:MicroRNA dbr:GALNT1 dbr:Medulloblastoma dbr:Gene_expression dbr:SOX4 dbr:Endometrial_cancer dbr:Gastric_cancer dbr:Gene dbc:MicroRNA_precursor_families dbr:Zebrafish dbr:Adenomatous_polyposis_coli dbr:Eukaryota dbr:Dicer dbr:Stem-loop dbr:Rat dbr:Sequence_conservation dbr:Non-coding_RNA dbr:RT-PCR dbr:Fragile_site dbr:Secondary_structure dbr:Cdk6 dbr:EIF2C3 dbr:Rab11
dbp:caption	Predicted secondary structure and sequence conservation of mir-129 (en)
dbp:id	RF00486 (en)
dbp:mirbase	MI0000252 (en)
dbp:mirbaseFamily	MIPF0000073 (en)
dbp:name	miR-129 microRNA precursor family (en) mir-129 microRNA precursor family (en)
dbp:rfam	RF00486 (en)
dbp:rnaType	dbr:MicroRNA dbr:Gene
dbp:symbol	mir-129 (en)
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rdfs:comment	The miR-129 microRNA precursor is a small non-coding RNA molecule that regulates gene expression. This microRNA was first experimentally characterised in mouse and homologues have since been discovered in several other species, such as humans, rats and zebrafish. The mature sequence is excised by the Dicer enzyme from the 5' arm of the hairpin. It was elucidated by Calin et al. that miR-129-1 is located in a fragile site region of the human genome near a specific site, FRA7H in chromosome 7q32, which is a site commonly deleted in many cancers. miR-129-2 is located in 11p11.2. (en)
rdfs:label	Mir-129 microRNA precursor family (en)
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