About: Melanocortin

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The melanocortins are a family of neuropeptide hormones which are the ligands of the melanocortin receptors The melanocortin system consists of melanocortin receptors, ligands, and accessory proteins. The genes of the melanocortin system are found in chordates. Melanocortins were originally named so because their earliest known function was in melanogenesis. It is now known that the melanocortin system regulates diverse functions throughout the body, including inflammatory response, fibrosis, melanogenesis, steroidogenesis, energy homeostasis, sexual function, and exocrine gland function.

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  • Les melanocortines és un grup d' que inclouen l'hormona adrenocorticotropa (ACTH) i les diferents formes de l' (MSH). Poden ser sintètiques (creades al laboratori). En els humans poden ésser endògenes, produïdes a partir de la (POMC) a la hipòfisi. Les melanocortines produeixen els seus efectes connectant-se i activant els . (ca)
  • Las melanocortinas​ son un grupo de hormonas peptídicas derivadas del polipéptido pro-opiomelanocortina, que incluyen a la hormona adrenocorticotropa (ACTH) y a las diferentes formas de la hormona estimulante de melanocitos (MSH), que a su vez comparten una familia de 5 receptores celulares. Las melanocortinas tienen funciones en: la pigmentación, la inflamación, la homeostasis energética y la función sexual.​ Pueden ser sintéticas (creadas en laboratorio).En humanos son endógenas, producidas a partir de la pro-opiomelanocortina (POMC) en la hipófisis.​Las melanocortinas producen sus efectos conectándose y activando los .​ (es)
  • The melanocortins are a family of neuropeptide hormones which are the ligands of the melanocortin receptors The melanocortin system consists of melanocortin receptors, ligands, and accessory proteins. The genes of the melanocortin system are found in chordates. Melanocortins were originally named so because their earliest known function was in melanogenesis. It is now known that the melanocortin system regulates diverse functions throughout the body, including inflammatory response, fibrosis, melanogenesis, steroidogenesis, energy homeostasis, sexual function, and exocrine gland function. There are four endogenous melanocortin agonists which are derived from post-transcriptional processing of the precursor molecule proopiomelanocortin (POMC) (Figure 1). They are Adrenocorticotropic hormone (ACTH), a-melanocyte stimulating hormone (MSH), b-MSH, and g-MSH. In addition to agonists which activate melanocortin receptors , there are two antagonists which inhibit receptor activity, Agouti and Agouti-related protein (Agrp). Lastly, the ligand β-defensin 3 acts as a neutral melanocortin receptor antagonist. (en)
  • 黑素皮质素(英語:melanocortin),也称促黑激素、促黑色素細胞激素、黑細胞促素等,是一类肽类激素,其中包含促腎上腺皮質激素(ACTH)和各类黑色素细胞刺激素(MSH)。这类激素由前腦啡黑細胞促素皮促素(POMC)在腦下垂體产生,通过结合并激活黑素皮质素受体(MCR)产生作用。黑素皮质素受体(MCR)共有5种,且均为G蛋白偶联受体:在大脑中仅表达MC3R与MC4R两种受体,二者配体为α-MSH,而(AgRP)是其内源性拮抗剂。 (zh)
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  • Les melanocortines és un grup d' que inclouen l'hormona adrenocorticotropa (ACTH) i les diferents formes de l' (MSH). Poden ser sintètiques (creades al laboratori). En els humans poden ésser endògenes, produïdes a partir de la (POMC) a la hipòfisi. Les melanocortines produeixen els seus efectes connectant-se i activant els . (ca)
  • 黑素皮质素(英語:melanocortin),也称促黑激素、促黑色素細胞激素、黑細胞促素等,是一类肽类激素,其中包含促腎上腺皮質激素(ACTH)和各类黑色素细胞刺激素(MSH)。这类激素由前腦啡黑細胞促素皮促素(POMC)在腦下垂體产生,通过结合并激活黑素皮质素受体(MCR)产生作用。黑素皮质素受体(MCR)共有5种,且均为G蛋白偶联受体:在大脑中仅表达MC3R与MC4R两种受体,二者配体为α-MSH,而(AgRP)是其内源性拮抗剂。 (zh)
  • The melanocortins are a family of neuropeptide hormones which are the ligands of the melanocortin receptors The melanocortin system consists of melanocortin receptors, ligands, and accessory proteins. The genes of the melanocortin system are found in chordates. Melanocortins were originally named so because their earliest known function was in melanogenesis. It is now known that the melanocortin system regulates diverse functions throughout the body, including inflammatory response, fibrosis, melanogenesis, steroidogenesis, energy homeostasis, sexual function, and exocrine gland function. (en)
  • Las melanocortinas​ son un grupo de hormonas peptídicas derivadas del polipéptido pro-opiomelanocortina, que incluyen a la hormona adrenocorticotropa (ACTH) y a las diferentes formas de la hormona estimulante de melanocitos (MSH), que a su vez comparten una familia de 5 receptores celulares. Las melanocortinas tienen funciones en: la pigmentación, la inflamación, la homeostasis energética y la función sexual.​ (es)
rdfs:label
  • Melanocortina (ca)
  • Melanocortina (es)
  • Melanocortin (en)
  • Melanocortina (pt)
  • 黑素皮质素 (zh)
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