About: Medrysone

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Medrysone (INN, USAN) (brand names HMS, Medrocort, others; former developmental code name NSC-63278), also known as hydroxymethylprogesterone, methylhydroxyprogesterone, or hydroxymesterone, as well as 6α-methyl-11β-hydroxyprogesterone or 6α-methyl-11β-hydroxypregn-4-ene-3,20-dione, is a synthetic glucocorticoid that is or has been used in the treatment of inflammatory eye diseases. It has been discontinued in the United States. Although it is very similar in structure to progesterone, neither progestogenic nor androgenic activity has been demonstrated for or attributed to medrysone.

Property	Value
dbo:abstract	Medrysone (INN, USAN) (brand names HMS, Medrocort, others; former developmental code name NSC-63278), also known as hydroxymethylprogesterone, methylhydroxyprogesterone, or hydroxymesterone, as well as 6α-methyl-11β-hydroxyprogesterone or 6α-methyl-11β-hydroxypregn-4-ene-3,20-dione, is a synthetic glucocorticoid that is or has been used in the treatment of inflammatory eye diseases. It has been discontinued in the United States. Although it is very similar in structure to progesterone, neither progestogenic nor androgenic activity has been demonstrated for or attributed to medrysone. (en) Il medrisone è un antinfiammatorio corticosteroide di sintesi, più precisamente un glucocorticoide, utilizzato in oftalmologia. Il farmaco viene venduto nella forma farmaceutica di sospensione oftalmica contenente l'1% di principio attivo. (it)
dbo:alternativeName	HMS, Medrocort, others (en)
dbo:casNumber	2668-66-8
dbo:chEMBL	1201173
dbo:drugbank	DB00253
dbo:fdaUniiCode	D2UFC189XF
dbo:kegg	D02289
dbo:medlinePlus	a606003
dbo:pubchem	247839
dbo:thumbnail	wiki-commons:Special:FilePath/Medrysone.svg?width=300
dbo:wikiPageID	6717142 (xsd:integer)
dbo:wikiPageLength	6090 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID	1089492788 (xsd:integer)
dbo:wikiPageWikiLink	dbr:California dbr:Progesterone dbr:Endrisone dbr:Progestogen dbr:Androgen dbr:United_States dbr:In_vitro dbr:Inflammation dbr:11β-Hydroxyprogesterone dbc:Diketones dbc:Glucocorticoids dbc:Pregnanes dbc:Secondary_alcohols dbr:Chemical_structure dbr:Estrogenic dbr:Fluorometholone dbr:Flugestone dbr:Glucocorticoid dbr:9α-Bromo-11-ketoprogesterone dbr:International_Nonproprietary_Name dbr:United_States_Adopted_Name dbr:Wastewater_treatment dbr:Eye_disease dbr:Synthetic_compound
dbp:atcPrefix	S01 (en)
dbp:atcSuffix	BA08 (en)
dbp:c	22 (xsd:integer)
dbp:casNumber	2668 (xsd:integer)
dbp:chembl	1201173 (xsd:integer)
dbp:chemspiderid	216968 (xsd:integer)
dbp:drugbank	DB00253 (en)
dbp:h	32 (xsd:integer)
dbp:iupacName	-17 (xsd:integer) 111214151617 (xsd:decimal)
dbp:iupharLigand	7086 (xsd:integer)
dbp:kegg	D02289 (en)
dbp:legalUsComment	Discontinued (en)
dbp:medlineplus	a606003 (en)
dbp:o	3 (xsd:integer)
dbp:pregnancyUs	C (en)
dbp:pubchem	247839 (xsd:integer)
dbp:routesOfAdministration	Eye drops (en)
dbp:smiles	C[C@H]1C[C@H]2[C@@H]3CC[C@@H]CC (en)
dbp:stdinchi	1 (xsd:integer)
dbp:stdinchikey	GZENKSODFLBBHQ-ILSZZQPISA-N (en)
dbp:synonyms	NSC-63278; Hydroxymethylprogesterone; Methylhydroxyprogesterone; Hydroxymesterone; 6α-Methyl-11β-hydroxyprogesterone; 6α-Methyl-11β-hydroxypregn-4-ene-3,20-dione (en)
dbp:tradename	HMS, Medrocort, others (en)
dbp:unii	D2UFC189XF (en)
dbp:verifiedfields	changed (en)
dbp:verifiedrevid	408087713 (xsd:integer)
dbp:watchedfields	changed (en)
dbp:width	250 (xsd:integer)
dbp:wikiPageUsesTemplate	dbt:Drugbox dbt:Glucocorticoid_receptor_modulators dbt:Reflist dbt:Short_description dbt:Steroid-stub dbt:Cascite dbt:Chemspidercite dbt:Drugbankcite dbt:Ebicite dbt:Fdacite dbt:Keggcite dbt:Stdinchicite dbt:Glucocorticoids_and_antiglucocorticoids dbt:Drugs.com
dcterms:subject	dbc:Diketones dbc:Glucocorticoids dbc:Pregnanes dbc:Secondary_alcohols
gold:hypernym	dbr:Corticosteroid
rdf:type	owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 yago:WikicatSteroids yago:Abstraction100002137 yago:Chemical114806838 yago:Compound114818238 yago:Material114580897 yago:Matter100020827 yago:OrganicCompound114727670 yago:Part113809207 yago:PhysicalEntity100001930 yago:Relation100031921 dbo:Drug yago:Steroid115057744 yago:Substance100019613 umbel-rc:DrugProduct
rdfs:comment	Medrysone (INN, USAN) (brand names HMS, Medrocort, others; former developmental code name NSC-63278), also known as hydroxymethylprogesterone, methylhydroxyprogesterone, or hydroxymesterone, as well as 6α-methyl-11β-hydroxyprogesterone or 6α-methyl-11β-hydroxypregn-4-ene-3,20-dione, is a synthetic glucocorticoid that is or has been used in the treatment of inflammatory eye diseases. It has been discontinued in the United States. Although it is very similar in structure to progesterone, neither progestogenic nor androgenic activity has been demonstrated for or attributed to medrysone. (en) Il medrisone è un antinfiammatorio corticosteroide di sintesi, più precisamente un glucocorticoide, utilizzato in oftalmologia. Il farmaco viene venduto nella forma farmaceutica di sospensione oftalmica contenente l'1% di principio attivo. (it)
rdfs:label	Medrisone (it) Medrysone (en)
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prov:wasDerivedFrom	wikipedia-en:Medrysone?oldid=1089492788&ns=0
foaf:depiction	wiki-commons:Special:FilePath/Medrysone.svg
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is dbo:wikiPageRedirects of	dbr:HMS_Liquifilm dbr:ATC_code_S01BA08 dbr:ATCvet_code_QS01BA08 dbr:Medrifar dbr:Medritonic dbr:Medrocort dbr:Visudrisone dbr:Hydroxymesterone dbr:Hydroxymethylprogesterone dbr:NSC-63,278 dbr:NSC-63278 dbr:NSC63,278 dbr:NSC63278 dbr:NSC_63,278 dbr:NSC_63278
is dbo:wikiPageWikiLink of	dbr:Endrisone dbr:List_of_corticosteroids dbr:HMS_Liquifilm dbr:C22H32O3 dbr:Bromoketoprogesterone dbr:Fluorometholone dbr:Flugestone dbr:HMS dbr:ATC_code_S01BA08 dbr:ATCvet_code_QS01BA08 dbr:ATC_code_S01 dbr:Vernal_keratoconjunctivitis dbr:Medrifar dbr:Medritonic dbr:Medrocort dbr:List_of_drugs:_Hf–Hz dbr:List_of_drugs:_Me–Meo dbr:Visudrisone dbr:Hydroxymesterone dbr:Hydroxymethylprogesterone dbr:NSC-63,278 dbr:NSC-63278 dbr:NSC63,278 dbr:NSC63278 dbr:NSC_63,278 dbr:NSC_63278
is foaf:primaryTopic of	wikipedia-en:Medrysone