About: MEK inhibitor

An Entity of Type: chemical compound, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

A MEK inhibitor is a chemical or drug that inhibits the mitogen-activated protein kinase kinase enzymes MEK1 and/or MEK2.They can be used to affect the MAPK/ERK pathway which is often overactive in some cancers. (See MAPK/ERK pathway#Clinical significance.) Hence MEK inhibitors have potential for treatment of some cancers, especially BRAF-mutated melanoma, and KRAS/BRAF mutated colorectal cancer.

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dbo:abstract
  • Ein MAP-Kinase-Inhibitor ist ein Hemmstoff des MAP-Kinase-Wegs und gehört als Tyrosinkinase-Inhibitor oder Serin/Threoninkinase-Inhibitor zu den Proteinkinaseinhibitoren. (de)
  • A MEK inhibitor is a chemical or drug that inhibits the mitogen-activated protein kinase kinase enzymes MEK1 and/or MEK2.They can be used to affect the MAPK/ERK pathway which is often overactive in some cancers. (See MAPK/ERK pathway#Clinical significance.) Hence MEK inhibitors have potential for treatment of some cancers, especially BRAF-mutated melanoma, and KRAS/BRAF mutated colorectal cancer. (en)
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  • Ein MAP-Kinase-Inhibitor ist ein Hemmstoff des MAP-Kinase-Wegs und gehört als Tyrosinkinase-Inhibitor oder Serin/Threoninkinase-Inhibitor zu den Proteinkinaseinhibitoren. (de)
  • A MEK inhibitor is a chemical or drug that inhibits the mitogen-activated protein kinase kinase enzymes MEK1 and/or MEK2.They can be used to affect the MAPK/ERK pathway which is often overactive in some cancers. (See MAPK/ERK pathway#Clinical significance.) Hence MEK inhibitors have potential for treatment of some cancers, especially BRAF-mutated melanoma, and KRAS/BRAF mutated colorectal cancer. (en)
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  • MAP-Kinase-Inhibitor (de)
  • MEK inhibitor (en)
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