About: MAFA

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MAFA (Mast cell function-associated antigen) is a , first identified on the surface of rat mucosal-type mast cells of the . More recently, human and mouse homologues of MAFA have been discovered yet also (or only) expressed by NK and T-cells. MAFA is closely linked with the in not only mucosal mast cells of humans and mice but also in the serosal mast cells of these same organisms.

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  • MAFA (Mast cell function-associated antigen) is a , first identified on the surface of rat mucosal-type mast cells of the . More recently, human and mouse homologues of MAFA have been discovered yet also (or only) expressed by NK and T-cells. MAFA is closely linked with the in not only mucosal mast cells of humans and mice but also in the serosal mast cells of these same organisms. It has the ability to function as both a channel for calcium ions along with interact with other receptors to inhibit certain cell processes. It function is based on its specialized structure, which contains many specialized motifs and sequences that allow its functions to take place. (en)
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  • MAFA (Mast cell function-associated antigen) is a , first identified on the surface of rat mucosal-type mast cells of the . More recently, human and mouse homologues of MAFA have been discovered yet also (or only) expressed by NK and T-cells. MAFA is closely linked with the in not only mucosal mast cells of humans and mice but also in the serosal mast cells of these same organisms. (en)
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  • MAFA (en)
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