About: Lymphokine

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Lymphokines are a subset of cytokines that are produced by a type of immune cell known as a lymphocyte. They are protein mediators typically produced by T cells to direct the immune system response by signaling between its cells. Lymphokines have many roles, including the attraction of other immune cells, including macrophages and other lymphocytes, to an infected site and their subsequent activation to prepare them to mount an immune response. Circulating lymphocytes can detect a very small concentration of lymphokine and then move up the concentration gradient towards where the immune response is required. Lymphokines aid B cells to produce antibodies.

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  • Lymphokine sind eine Sammelbezeichnung für spezielle Zytokine. Die ursprüngliche Definition von Dumonde (1982) bezeichnete alle nicht-Antikörper-Proteine, die von aktivierten Lymphozyten produziert werden und als interzellulare Botenstoffe der Immunantwort wirken, als Lymphokine. Diese Definition ist in mehrerer Hinsicht problematisch und wird seit den 1990er-Jahren kaum noch verwendet. Zwei bedeutende Stoffklassen, die zu den Lymphokinen gehören, sind die Interleukine und die Interferone. Die ersten Lymphokine wurden Mitte der 1960er-Jahre identifiziert, wobei der am besten untersuchte Migration Inhibition Factor (MIF) gleichzeitig von und Barry Bloom beschrieben wurde. (de)
  • Las linfocinas son una familia de moléculas pertenecientes a las interleucinas (que a su vez pertenecen a las citocinas o mensajeros químicos), que son producidas y liberadas por las células denominadas linfocitos T. Las linfocinas son sustancias polipeptídicas sintetizadas por linfocitos que afectan a la función de otros tipos celulares mediante acción paracrina o autocrina. La acción de las linfoquinas es muy variada, pudiendo estimular o inhibir diferentes aspectos de la respuesta inmunitaria. Su función es atraer a las células macrófagos al lugar en que se ha producido una infección o inflamación, además de prepararlos para el ataque a los posibles invasores extraños que estén produciendo dicha infección. Ejemplos de linfocinas son: * el factor inhibidor del macrófago, * el factor mitogenético * la linfotoxina. * las interleuquinas 1 y 2, * el interferón gamma. (es)
  • Lymphokines are a subset of cytokines that are produced by a type of immune cell known as a lymphocyte. They are protein mediators typically produced by T cells to direct the immune system response by signaling between its cells. Lymphokines have many roles, including the attraction of other immune cells, including macrophages and other lymphocytes, to an infected site and their subsequent activation to prepare them to mount an immune response. Circulating lymphocytes can detect a very small concentration of lymphokine and then move up the concentration gradient towards where the immune response is required. Lymphokines aid B cells to produce antibodies. Important lymphokines secreted by the T helper cell include: * Interleukin 2 * Interleukin 3 * Interleukin 4 * Interleukin 5 * Interleukin 6 * Granulocyte-macrophage colony-stimulating factor * Interferon-gamma (en)
  • 림포카인(영어: lymphokine)은 사이토카인의 부분집합으로, 림프구에 의해 생성된다. 이들은 T세포에 의해 생성되는 단백질 중재자로, 세포 사이의 신호전달을 통해 면역계 반응을 지시한다. 림포카인은 감염부위로 대식세포와 다른 림프구를 유도하고 면역 반응을 일으키도록 활성화시키는 등의 많은 역할을 한다. 순환하는 림프구들은 림포카인의 아주 작은 양도 감지할 수 있고 농도 구배를 따라 면역 반응을 필요로 하는 곳으로 이동한다. 림포카인은 B세포가 항체를 생성하도록 도와준다. 주요한 림포카인들은 보조 T 세포에 의해 분비되는데, 그 종류는 다음과 같다. * * * 인터루킨 4 * * 인터루킨 6 * 과립구 대식세포 콜로니 자극 인자 * 인터페론 감마 (ko)
  • 淋巴因子(Lymphokine)是细胞因子的一亚类,指由淋巴细胞产生的细胞因子,属于多肽类介质。通常是由T细胞产生的通过影响其他免疫细胞的功能而改变免疫系统的反应;例如吸引巨噬细胞及其他淋巴细胞至感染处,随后激活它们使之准备发动免疫反应;又如协助B细胞制造抗体。 这一术语已经过时,因为后续发现相同因子可由非淋巴细胞分泌,所以现常统称为细胞因子。 (zh)
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  • 림포카인(영어: lymphokine)은 사이토카인의 부분집합으로, 림프구에 의해 생성된다. 이들은 T세포에 의해 생성되는 단백질 중재자로, 세포 사이의 신호전달을 통해 면역계 반응을 지시한다. 림포카인은 감염부위로 대식세포와 다른 림프구를 유도하고 면역 반응을 일으키도록 활성화시키는 등의 많은 역할을 한다. 순환하는 림프구들은 림포카인의 아주 작은 양도 감지할 수 있고 농도 구배를 따라 면역 반응을 필요로 하는 곳으로 이동한다. 림포카인은 B세포가 항체를 생성하도록 도와준다. 주요한 림포카인들은 보조 T 세포에 의해 분비되는데, 그 종류는 다음과 같다. * * * 인터루킨 4 * * 인터루킨 6 * 과립구 대식세포 콜로니 자극 인자 * 인터페론 감마 (ko)
  • 淋巴因子(Lymphokine)是细胞因子的一亚类,指由淋巴细胞产生的细胞因子,属于多肽类介质。通常是由T细胞产生的通过影响其他免疫细胞的功能而改变免疫系统的反应;例如吸引巨噬细胞及其他淋巴细胞至感染处,随后激活它们使之准备发动免疫反应;又如协助B细胞制造抗体。 这一术语已经过时,因为后续发现相同因子可由非淋巴细胞分泌,所以现常统称为细胞因子。 (zh)
  • Lymphokine sind eine Sammelbezeichnung für spezielle Zytokine. Die ursprüngliche Definition von Dumonde (1982) bezeichnete alle nicht-Antikörper-Proteine, die von aktivierten Lymphozyten produziert werden und als interzellulare Botenstoffe der Immunantwort wirken, als Lymphokine. Diese Definition ist in mehrerer Hinsicht problematisch und wird seit den 1990er-Jahren kaum noch verwendet. (de)
  • Las linfocinas son una familia de moléculas pertenecientes a las interleucinas (que a su vez pertenecen a las citocinas o mensajeros químicos), que son producidas y liberadas por las células denominadas linfocitos T. Las linfocinas son sustancias polipeptídicas sintetizadas por linfocitos que afectan a la función de otros tipos celulares mediante acción paracrina o autocrina. La acción de las linfoquinas es muy variada, pudiendo estimular o inhibir diferentes aspectos de la respuesta inmunitaria. Ejemplos de linfocinas son: (es)
  • Lymphokines are a subset of cytokines that are produced by a type of immune cell known as a lymphocyte. They are protein mediators typically produced by T cells to direct the immune system response by signaling between its cells. Lymphokines have many roles, including the attraction of other immune cells, including macrophages and other lymphocytes, to an infected site and their subsequent activation to prepare them to mount an immune response. Circulating lymphocytes can detect a very small concentration of lymphokine and then move up the concentration gradient towards where the immune response is required. Lymphokines aid B cells to produce antibodies. (en)
rdfs:label
  • Lymphokine (de)
  • Linfocina (es)
  • Lymphokine (en)
  • 림포카인 (ko)
  • 淋巴因子 (zh)
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