The following list contains the most notable road interchanges within the United States divided by each state, which are mainly part of the national Interstate Highway System and are all freeways intersecting with each other at a junction. Some of the biggest ones are: Kennedy Interchange (I-64/I-65/I-71) in Louisville, Kentucky; the Marquette Interchange (I-94/I-43/I-794) and the $1.8 billion Zoo Interchange both in Milwaukee, Wisconsin; the Pregerson Interchange (I-110/I-105) in Los Angeles; and the Circle Interchange (I-90/I-94/I-290) in Chicago.
