About: Larazotide

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Larazotide (INN; also known as AT-1001; formulated as the salt with acetic acid, larazotide acetate) is a synthetic eight amino acid peptide that functions as a tight junction regulator and reverses leaky junctions to their normally closed state. It is being studied in people with celiac disease.

Property	Value
dbo:abstract	Larazotide (INN; also known as AT-1001; formulated as the salt with acetic acid, larazotide acetate) is a synthetic eight amino acid peptide that functions as a tight junction regulator and reverses leaky junctions to their normally closed state. It is being studied in people with celiac disease. (en)
dbo:casNumber	258818-34-7 881851-50-9 (acetate)
dbo:fdaUniiCode	ZN3R5560ZV
dbo:kegg	D09351
dbo:pubchem	9810532
dbo:thumbnail	wiki-commons:Special:FilePath/Larazotide.svg?width=300
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dbo:wikiPageWikiLink	dbr:Enterotoxin dbr:Epidermal_growth_factor_receptor dbr:MYD88 dbr:Peptide dbr:Rheumatoid_arthritis dbr:International_nonproprietary_name dbr:Intestinal_permeability dbr:Protease-activated_receptor_2 dbc:Experimental_drugs dbr:Vibrio_cholerae dbr:Coeliac_disease dbr:Peptide_synthesis dbr:Acetic_acid dbr:Amino_acid dbr:Cell_culture dbr:Gliadin dbr:Gluten_immunochemistry dbr:International_Union_of_Pure_and_Applied_Chemistry dbc:Peptides dbc:Drugs_acting_on_the_gastrointestinal_system_and_metabolism dbr:Chemokine dbr:C-terminus dbr:CXCR3 dbr:Lumen_(anatomy) dbr:Salt_(chemistry) dbr:Immune_system dbr:Tight_junction dbr:Zonulin dbr:</nowiki>(2''S'')-1-[(2''S'')-5-amino-...rolidine-2-carbonyl]amino]acetic_acid
dbp:c	32 (xsd:integer)
dbp:casNumber	258818 (xsd:integer)
dbp:casSupplemental	881851 (xsd:integer)
dbp:chemspiderid	7986288 (xsd:integer)
dbp:h	55 (xsd:integer)
dbp:iupacName	2 (xsd:integer)
dbp:kegg	D09351 (en)
dbp:legalStatus	Investigational (en)
dbp:n	9 (xsd:integer)
dbp:o	10 (xsd:integer)
dbp:pubchem	9810532 (xsd:integer)
dbp:smiles	CCC[C@@H]NC[C@H]NCCNCCN (en)
dbp:stdinchi	1 (xsd:integer)
dbp:stdinchikey	ORFLZNAGUTZRLQ-ZMBVWFSWSA-N (en)
dbp:unii	ZN3R5560ZV (en)
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rdfs:comment	Larazotide (INN; also known as AT-1001; formulated as the salt with acetic acid, larazotide acetate) is a synthetic eight amino acid peptide that functions as a tight junction regulator and reverses leaky junctions to their normally closed state. It is being studied in people with celiac disease. (en)
rdfs:label	Larazotide (en)
owl:sameAs	yago-res:Larazotide wikidata:Larazotide https://global.dbpedia.org/id/2PNUY
prov:wasDerivedFrom	wikipedia-en:Larazotide?oldid=1092619673&ns=0
foaf:depiction	wiki-commons:Special:FilePath/Larazotide.svg
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