Khaneh Khamis-e Olya (Persian: خانه خميس عليا, also Romanized as Khāneh Khamīs-e ‘Olyā; also known as Khānkhamīs-e ‘Olyā) is a village in Siyakh Darengun Rural District, in the Central District of Shiraz County, Fars Province, Iran. At the 2006 census, its population was 583, in 128 families.