About: Juvenile hormone epoxide hydrolase

An Entity of Type: protein, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Juvenile hormone epoxide hydrolase (JHEH) is an enzyme that inactivates insect juvenile hormones. This inactivation is accomplished through hydrolysis of the epoxide functional group contained within these hormones into diols. JHEH is one of two enzymes involved in the termination of signaling properties of the various juvenile hormones. The other is juvenile-hormone esterase, or JHE. The first observation of activity from JHEH was in Rhodnius prolixus and Schistocerca gregaria. JH esterase was also first observed in this same work.

Property	Value
dbo:abstract	Juvenile hormone epoxide hydrolase (JHEH) is an enzyme that inactivates insect juvenile hormones. This inactivation is accomplished through hydrolysis of the epoxide functional group contained within these hormones into diols. JHEH is one of two enzymes involved in the termination of signaling properties of the various juvenile hormones. The other is juvenile-hormone esterase, or JHE. The first observation of activity from JHEH was in Rhodnius prolixus and Schistocerca gregaria. JH esterase was also first observed in this same work. (en)
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dbo:wikiPageWikiLink	dbr:Catalytic_triad dbr:Schistocerca_gregaria dbr:Epoxide dbr:Bombyx_mori dbc:EC_3.3.2 dbr:Manduca_sexta dbr:RNA_interference dbr:Enzyme dbr:Leptinotarsa_decemlineata dbr:Juvenile-hormone_esterase dbr:Juvenile_hormone dbr:Juvenile_hormone_diol_kinase dbr:Esterification dbr:Carboxylic_acid dbr:Diol dbr:Phosphate dbr:Microsomal_epoxide_hydrolase dbr:Rhodnius_prolixus dbr:Trichoplusia_ni dbr:Hydroxyl_group
dbp:altsymbols	Jheh2 (en)
dbp:caption	Crystal structure of juvenile hormone epoxide hydrolase from the silkworm Bombyx mori. (en)
dbp:chromosome	shotgun (en)
dbp:ecnumber	3.300000 (xsd:double)
dbp:entrezchromosome	NW_004582036.1 (en)
dbp:entrezgene	692686 (xsd:integer)
dbp:genlocEnd	648456 (xsd:integer)
dbp:genlocStart	632321 (xsd:integer)
dbp:name	Juvenile hormone epoxide hydrolase (en)
dbp:organism	Bombyx mori (en)
dbp:pdb	4 (xsd:integer)
dbp:refseqmrna	NM_001043736.1 (en)
dbp:refseqprotein	NP_001037201.1 (en)
dbp:symbol	JHEH (en)
dbp:taxid	7091 (xsd:integer)
dbp:uniprot	Q6U6J0 (en)
dbp:wikiPageUsesTemplate	dbt:Enzymes dbt:Infobox_nonhuman_protein dbt:Portal_bar dbt:Reflist dbt:Ether_bond_hydrolases
dcterms:subject	dbc:EC_3.3.2
gold:hypernym	dbr:Enzyme
rdf:type	dbo:Protein
rdfs:comment	Juvenile hormone epoxide hydrolase (JHEH) is an enzyme that inactivates insect juvenile hormones. This inactivation is accomplished through hydrolysis of the epoxide functional group contained within these hormones into diols. JHEH is one of two enzymes involved in the termination of signaling properties of the various juvenile hormones. The other is juvenile-hormone esterase, or JHE. The first observation of activity from JHEH was in Rhodnius prolixus and Schistocerca gregaria. JH esterase was also first observed in this same work. (en)
rdfs:label	Juvenile hormone epoxide hydrolase (en)
owl:sameAs	wikidata:Juvenile hormone epoxide hydrolase https://global.dbpedia.org/id/2LFAF
prov:wasDerivedFrom	wikipedia-en:Juvenile_hormone_epoxide_hydrolase?oldid=977259433&ns=0
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is dbo:wikiPageWikiLink of	dbr:Juvenile_hormone dbr:Juvenile_hormone_diol_kinase
is foaf:primaryTopic of	wikipedia-en:Juvenile_hormone_epoxide_hydrolase