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- John E. Heuser (* 29. August 1942 in Pittsburgh, Pennsylvania) ist ein US-amerikanischer Zellbiologe und Biophysiker. Er ist Professor an der Medizinischen Fakultät der Washington University in St. Louis und am Institute for Integrated Cell-Material Sciences (iCeMS) in Kyōto. Er ist bekannt für die Entwicklung eines Schnellgefrierverfahrens für Präparate in der Elektronenmikroskopie, mit anschließendem Aufdampfen einer Platin-Schicht (Freeze etch electron microscopy). Er studierte damit z. B. Muskelkontraktion, Ausbreitung von Nervenimpulsen und Eindringen von Viren in Zellen. Von 1975 bis 1998 war er Instructor in den Sommerkursen für Neurobiologie in Woods Hole. Heuser studierte an der Harvard Medical School mit der Promotion 1969 (M. D., magna cum laude). Er war dort im Labor für Elektronenmikroskopie von J. David Robertson. Als Post-Doktorand war er bei Bernard Katz und Ricardo Miledi am University College London. 1974 wurde er Assistant Professor und später Professor für Physiologie an der University of California, San Francisco. Ab 1980 war er Professor für Biophysik an der Washington University School of Medicine. 2014 erhielt er die E. B. Wilson Medal und 1980 hielt er die W. Alden Spencer Lecture, 1985 die Keith R. Porter Lecture. 2005 wurde er Fellow der American Academy of Arts and Sciences, 2007 der American Association for the Advancement of Science und 2011 der National Academy of Sciences. (de)
- John E. Heuser (born August 29, 1942) is an American Professor of Biophysics in the department of Cell Biology and Physiology at the Washington University School of Medicine as well as a Professor at the Institute for Integrated Cell-Matieral Sciences (iCeMS) at Kyoto University. Heuser created quick-freeze deep-etch electron microscopy (a variant of cell unroofing), a pioneering technique that lets biologists take detailed pictures of fleeting events inside living cells. For decades, Heuser has used this technique to capture details of the molecular mechanisms that underlie many basic biological activities, including nerve cell signal transmission, muscle contraction, and most recently, the fusion of viruses with cells during the spread of infection. He compares quick-freeze deep-etch electron microscopy to using a stroboscopic flash to freeze the action in a photograph. To make it possible to image the frozen sample with an electron microscope, Heuser adds an ultra-thin film of metallic platinum that molds snugly against the sample's frozen surface contours. He and others in his lab have worked to make the equipment and procedures necessary for this process available to researchers around the world. Currently Heuser has patents pending on Washington University's behalf for even more advanced versions of his quick-freezing machines. Heuser graduated magna cum laude from Harvard Medical School in 1969 and joined the Washington University faculty as a professor of biophysics in 1980. He is currently associate editor of the Journal of Neurocytology and previously served as associate editor of the Journal of Cell Biology. His curriculum vitae lists over 200 scientific publications. He was elected as a fellow of the American Academy of Arts and Sciences class of 2005 and of the American Association for the Advancement of Science in 2007. Heuser was also elected as a member of the National Academy of Sciences in 2011. (en)
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- Pittsburgh, Pennsylvania (en)
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- John E. Heuser (* 29. August 1942 in Pittsburgh, Pennsylvania) ist ein US-amerikanischer Zellbiologe und Biophysiker. Er ist Professor an der Medizinischen Fakultät der Washington University in St. Louis und am Institute for Integrated Cell-Material Sciences (iCeMS) in Kyōto. 2014 erhielt er die E. B. Wilson Medal und 1980 hielt er die W. Alden Spencer Lecture, 1985 die Keith R. Porter Lecture. 2005 wurde er Fellow der American Academy of Arts and Sciences, 2007 der American Association for the Advancement of Science und 2011 der National Academy of Sciences. (de)
- John E. Heuser (born August 29, 1942) is an American Professor of Biophysics in the department of Cell Biology and Physiology at the Washington University School of Medicine as well as a Professor at the Institute for Integrated Cell-Matieral Sciences (iCeMS) at Kyoto University. (en)
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- John Heuser (de)
- John Heuser (en)
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