About: Interleukin-17 receptor

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Interleukin-17 receptor (IL-17R) is a cytokine receptor which belongs to new subfamily of receptors binding proinflammatory cytokine interleukin 17A, a member of IL-17 family ligands produced by T helper 17 cells (Th17). IL-17R family consists of 5 members: IL-17RA, IL-17RB, IL-17RC, IL-17RD and . Functional IL-17R is a transmembrane receptor complex usually consisting of one IL-17RA, which is a founding member of the family, and second other family subunit, thus forming heteromeric receptor binding different ligands. IL-17A, a founding member of IL-17 ligand family binds to heteromeric IL-17RA/RC receptor complex. IL-17RB binds preferentially IL-17B and IL-17E and heteromeric IL-17RA/RE complex binds IL-17C. However, there is still unknown ligand for IL-17RD. The first identified member I

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dbo:abstract
  • Interleukin-17 receptor (IL-17R) is a cytokine receptor which belongs to new subfamily of receptors binding proinflammatory cytokine interleukin 17A, a member of IL-17 family ligands produced by T helper 17 cells (Th17). IL-17R family consists of 5 members: IL-17RA, IL-17RB, IL-17RC, IL-17RD and . Functional IL-17R is a transmembrane receptor complex usually consisting of one IL-17RA, which is a founding member of the family, and second other family subunit, thus forming heteromeric receptor binding different ligands. IL-17A, a founding member of IL-17 ligand family binds to heteromeric IL-17RA/RC receptor complex. IL-17RB binds preferentially IL-17B and IL-17E and heteromeric IL-17RA/RE complex binds IL-17C. However, there is still unknown ligand for IL-17RD. The first identified member IL-17RA is located on human chromosome 22, whereas other subunits IL-17RB to IL-17RD are encoded within human chromosome 3. (en)
dbo:arm
  • p
  • q
dbo:band
  • 21.1
  • 25.3
  • 11.1
  • 13.33
dbo:chromosome
  • 3
  • 22
dbo:entrezgene
  • 132014
  • 23765
  • 400935
  • 54756
  • 55540
  • 84818
dbo:hgncid
  • 18015
  • 5985
  • 17616
  • 18358
  • 18439
  • 33808
dbo:omim
  • 605458 (xsd:integer)
  • 605461 (xsd:integer)
  • 606807 (xsd:integer)
  • 610925 (xsd:integer)
dbo:refseq
  • NM_001001694
  • NM_014339
  • NM_017563
  • NM_032732
  • NM_153480
  • NM_172234
dbo:symbol
  • FLJ23658
  • IL17-RL
  • IL17BR
  • IL17R
  • IL17R, CDw217
  • IL17RA
  • IL17RB
  • IL17RC
  • IL17RD
  • IL17RE
  • IL17REL
  • SEF, IL17RLM, FLJ35755, IL-17RD
dbo:thumbnail
dbo:uniprot
  • Q6ZVW7
  • Q8NAC3
  • Q8NFM7
  • Q8NFR9
  • Q96F46
  • Q9NRM6
dbo:wikiPageExternalLink
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  • 16036908 (xsd:integer)
dbo:wikiPageLength
  • 20855 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID
  • 1121534687 (xsd:integer)
dbo:wikiPageWikiLink
dbp:altsymbols
  • FLJ23658 (en)
  • IL17-RL (en)
  • IL17BR (en)
  • IL17R, CDw217 (en)
  • SEF, IL17RLM, FLJ35755, IL-17RD (en)
dbp:arm
  • p (en)
  • q (en)
dbp:band
  • 11.100000 (xsd:double)
  • 13.330000 (xsd:double)
  • 21.100000 (xsd:double)
  • 25.300000 (xsd:double)
dbp:caption
  • Crystal structure of a complex of IL-17RA bound to IL-17F in a 1:2 stoichiometry. (en)
dbp:chromosome
  • 3 (xsd:integer)
  • 22 (xsd:integer)
dbp:entrezgene
  • 23765 (xsd:integer)
  • 54756 (xsd:integer)
  • 55540 (xsd:integer)
  • 84818 (xsd:integer)
  • 132014 (xsd:integer)
  • 400935 (xsd:integer)
dbp:hgncid
  • 5985 (xsd:integer)
  • 17616 (xsd:integer)
  • 18015 (xsd:integer)
  • 18358 (xsd:integer)
  • 18439 (xsd:integer)
  • 33808 (xsd:integer)
dbp:interpro
  • IPR013568 (en)
dbp:membranomeSuperfamily
  • 8 (xsd:integer)
dbp:name
dbp:omim
  • 605458 (xsd:integer)
  • 605461 (xsd:integer)
  • 606807 (xsd:integer)
  • 610925 (xsd:integer)
dbp:pfam
  • PF08357 (en)
dbp:refseq
  • NM_001001694 (en)
  • NM_014339 (en)
  • NM_017563 (en)
  • NM_032732 (en)
  • NM_153480 (en)
  • NM_172234 (en)
dbp:symbol
dbp:uniprot
  • Q6ZVW7 (en)
  • Q8NAC3 (en)
  • Q8NFM7 (en)
  • Q8NFR9 (en)
  • Q96F46 (en)
  • Q9NRM6 (en)
dbp:wikiPageUsesTemplate
dcterms:subject
gold:hypernym
rdf:type
rdfs:comment
  • Interleukin-17 receptor (IL-17R) is a cytokine receptor which belongs to new subfamily of receptors binding proinflammatory cytokine interleukin 17A, a member of IL-17 family ligands produced by T helper 17 cells (Th17). IL-17R family consists of 5 members: IL-17RA, IL-17RB, IL-17RC, IL-17RD and . Functional IL-17R is a transmembrane receptor complex usually consisting of one IL-17RA, which is a founding member of the family, and second other family subunit, thus forming heteromeric receptor binding different ligands. IL-17A, a founding member of IL-17 ligand family binds to heteromeric IL-17RA/RC receptor complex. IL-17RB binds preferentially IL-17B and IL-17E and heteromeric IL-17RA/RE complex binds IL-17C. However, there is still unknown ligand for IL-17RD. The first identified member I (en)
rdfs:label
  • Interleukin-17 receptor (en)
owl:sameAs
prov:wasDerivedFrom
foaf:depiction
foaf:isPrimaryTopicOf
foaf:name
  • Interleukin 17 receptor D (en)
  • Interleukin 17 receptor E-like (en)
  • interleukin 17 receptor A (en)
  • interleukin 17 receptor B (en)
  • interleukin 17 receptor C (en)
  • interleukin 17 receptor E (en)
is dbo:wikiPageRedirects of
is dbo:wikiPageWikiLink of
is rdfs:seeAlso of
is foaf:primaryTopic of
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