About: Indo-1

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Indo-1 is a popular calcium indicator similar to Fura-2. In contrast to Fura-2, Indo-1 has a dual emissions peak. The main emission peak in calcium-free solution is 475 nm while in the presence of calcium the emission is shifted to 400 nm. It is widely used in flow cytometry.The penta potassium salt is commercially available and preferred to the free acid because of its higher solubility in water. While Indo-1 is not cell permeable the penta enters the cell where it is cleaved by intracellular esterases to Indo-1.The synthesis and properties of Indo-1 were presented in 1985 by the group of Roger Y Tsien.

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dbo:abstract
  • Indo-1 ist ein Fluoreszenzfarbstoff, der in Anwesenheit von Calciumionen seine optischen Eigenschaften ändert und daher als Calcium-Indikator verwendet wird. (de)
  • Indo-1 is a popular calcium indicator similar to Fura-2. In contrast to Fura-2, Indo-1 has a dual emissions peak. The main emission peak in calcium-free solution is 475 nm while in the presence of calcium the emission is shifted to 400 nm. It is widely used in flow cytometry.The penta potassium salt is commercially available and preferred to the free acid because of its higher solubility in water. While Indo-1 is not cell permeable the penta enters the cell where it is cleaved by intracellular esterases to Indo-1.The synthesis and properties of Indo-1 were presented in 1985 by the group of Roger Y Tsien. (en)
  • Indo-1 é um composto orgânico popular similar ao . Em contraste com o Fura-2, Indo-1 tem um duplo pico de emissão. (pt)
dbo:alternativeName
  • Indo-1 (en)
dbo:iupacName
  • 2-[4-(bis(carboxymethyl)amino)-3-[2-[2-(bis(carboxymethyl)amino)-]5-methylphenoxy]ethoxy]phenyl]-1H-indole-6-carboxylic acid (en)
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  • 4172 (xsd:nonNegativeInteger)
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  • 1059928310 (xsd:integer)
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  • Indo-1.svg (en)
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  • 250 (xsd:integer)
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  • 2 (xsd:integer)
dbp:othernames
  • Indo-1 (en)
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  • 443873843 (xsd:integer)
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  • changed (en)
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  • Indo-1 ist ein Fluoreszenzfarbstoff, der in Anwesenheit von Calciumionen seine optischen Eigenschaften ändert und daher als Calcium-Indikator verwendet wird. (de)
  • Indo-1 is a popular calcium indicator similar to Fura-2. In contrast to Fura-2, Indo-1 has a dual emissions peak. The main emission peak in calcium-free solution is 475 nm while in the presence of calcium the emission is shifted to 400 nm. It is widely used in flow cytometry.The penta potassium salt is commercially available and preferred to the free acid because of its higher solubility in water. While Indo-1 is not cell permeable the penta enters the cell where it is cleaved by intracellular esterases to Indo-1.The synthesis and properties of Indo-1 were presented in 1985 by the group of Roger Y Tsien. (en)
  • Indo-1 é um composto orgânico popular similar ao . Em contraste com o Fura-2, Indo-1 tem um duplo pico de emissão. (pt)
rdfs:label
  • Indo-1 (de)
  • Indo-1 (en)
  • Indo-1 (pt)
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