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I-set domains are found in several cell adhesion molecules, including vascular (VCAM), intercellular (ICAM), neural (NCAM) and mucosal addressin (MADCAM) cell adhesion molecules, as well as junction adhesion molecules (JAM). I-set domains are also present in several other diverse protein families, including several tyrosine-protein kinase receptors, the hemolymph protein hemolin, the muscle proteins titin, telokin, and twitchin, the neuronal adhesion molecule axonin-1, and the signalling molecule semaphorin 4D that is involved in axonal guidance, immune function and angiogenesis.

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dbo:abstract
  • I-set domains are found in several cell adhesion molecules, including vascular (VCAM), intercellular (ICAM), neural (NCAM) and mucosal addressin (MADCAM) cell adhesion molecules, as well as junction adhesion molecules (JAM). I-set domains are also present in several other diverse protein families, including several tyrosine-protein kinase receptors, the hemolymph protein hemolin, the muscle proteins titin, telokin, and twitchin, the neuronal adhesion molecule axonin-1, and the signalling molecule semaphorin 4D that is involved in axonal guidance, immune function and angiogenesis. (en)
dbo:symbol
  • I-set
dbo:thumbnail
dbo:wikiPageID
  • 24624735 (xsd:integer)
dbo:wikiPageLength
  • 4746 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID
  • 1107996929 (xsd:integer)
dbo:wikiPageWikiLink
dbp:caption
  • Structures of fibroblast growth factor 1. (en)
dbp:interpro
  • IPR013098 (en)
dbp:name
  • Immunoglobulin I-set domain (en)
dbp:pdb
  • B:327-412 A:322-407 C:159-247 B:20-114 D:159-247 A:42-132 C:159-247 A:652-767 A:214-304 A:25-112 :6585-6674 A:363-448 E:153-241 A:214-305 B:157-245 :42-132 :33489-3357 :33489-3357 A:43-113 A:25-112 A:25-112 A:306-320 :4150-4239 :4150-4239 A:325-352 A:342-430 A:1238-1327 A:419-516 :20-114 (en)
dbp:pfam
  • PF07679 (en)
dbp:symbol
  • I-set (en)
dbp:wikiPageUsesTemplate
dcterms:subject
rdf:type
rdfs:comment
  • I-set domains are found in several cell adhesion molecules, including vascular (VCAM), intercellular (ICAM), neural (NCAM) and mucosal addressin (MADCAM) cell adhesion molecules, as well as junction adhesion molecules (JAM). I-set domains are also present in several other diverse protein families, including several tyrosine-protein kinase receptors, the hemolymph protein hemolin, the muscle proteins titin, telokin, and twitchin, the neuronal adhesion molecule axonin-1, and the signalling molecule semaphorin 4D that is involved in axonal guidance, immune function and angiogenesis. (en)
rdfs:label
  • Immunoglobulin I-set domain (en)
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