About: H3R8me2

An Entity of Type: Thing, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

H3R8me2 is an epigenetic modification to the DNA packaging protein histone H3. It is a mark that indicates the di-methylation at the 8th arginine residue of the histone H3 protein. In epigenetics, arginine methylation of histones H3 and H4 is associated with a more accessible chromatin structure and thus higher levels of transcription. The existence of arginine demethylases that could reverse arginine methylation is controversial. H3R8me2 is associated with transcriptional repression, and modified by PRMT5, but not CARM1. As of March 2021, there are no disease associations known for H3R8me2.

thumbnail
Property Value
dbo:abstract
  • H3R8me2 is an epigenetic modification to the DNA packaging protein histone H3. It is a mark that indicates the di-methylation at the 8th arginine residue of the histone H3 protein. In epigenetics, arginine methylation of histones H3 and H4 is associated with a more accessible chromatin structure and thus higher levels of transcription. The existence of arginine demethylases that could reverse arginine methylation is controversial. H3R8me2 is associated with transcriptional repression, and modified by PRMT5, but not CARM1. As of March 2021, there are no disease associations known for H3R8me2. (en)
dbo:thumbnail
dbo:wikiPageID
  • 67209354 (xsd:integer)
dbo:wikiPageLength
  • 16711 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID
  • 1032036829 (xsd:integer)
dbo:wikiPageWikiLink
dbp:wikiPageUsesTemplate
dcterms:subject
rdfs:comment
  • H3R8me2 is an epigenetic modification to the DNA packaging protein histone H3. It is a mark that indicates the di-methylation at the 8th arginine residue of the histone H3 protein. In epigenetics, arginine methylation of histones H3 and H4 is associated with a more accessible chromatin structure and thus higher levels of transcription. The existence of arginine demethylases that could reverse arginine methylation is controversial. H3R8me2 is associated with transcriptional repression, and modified by PRMT5, but not CARM1. As of March 2021, there are no disease associations known for H3R8me2. (en)
rdfs:label
  • H3R8me2 (en)
owl:sameAs
prov:wasDerivedFrom
foaf:depiction
foaf:isPrimaryTopicOf
is dbo:wikiPageWikiLink of
is foaf:primaryTopic of
Powered by OpenLink Virtuoso    This material is Open Knowledge     W3C Semantic Web Technology     This material is Open Knowledge    Valid XHTML + RDFa
This content was extracted from Wikipedia and is licensed under the Creative Commons Attribution-ShareAlike 3.0 Unported License