About: GrpE

An Entity of Type: protein, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

GrpE (Gro-P like protein E) is a bacterial nucleotide exchange factor that is important for regulation of protein folding machinery, as well as the heat shock response. It is a heat-inducible protein and during stress it prevents unfolded proteins from accumulating in the cytoplasm. Accumulation of unfolded proteins in the cytoplasm can lead to cell death.

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dbo:abstract
  • GrpE (Gro-P like protein E) is a bacterial nucleotide exchange factor that is important for regulation of protein folding machinery, as well as the heat shock response. It is a heat-inducible protein and during stress it prevents unfolded proteins from accumulating in the cytoplasm. Accumulation of unfolded proteins in the cytoplasm can lead to cell death. (en)
dbo:symbol
  • GrpE
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  • 59989290 (xsd:integer)
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  • 22388 (xsd:nonNegativeInteger)
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  • 1095826337 (xsd:integer)
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  • Crystal structure of GrpE homodimer interacting with ATPase binding site of DnaK, resolved at 2.8 angstrom. (en)
dbp:cdd
  • cd00446 (en)
dbp:interpro
  • IPR000740 (en)
dbp:name
  • GrpE Protein (en)
dbp:pfam
  • PF01025 (en)
dbp:prosite
  • PS01071 (en)
dbp:scop
  • 1 (xsd:integer)
dbp:symbol
  • GrpE (en)
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rdfs:comment
  • GrpE (Gro-P like protein E) is a bacterial nucleotide exchange factor that is important for regulation of protein folding machinery, as well as the heat shock response. It is a heat-inducible protein and during stress it prevents unfolded proteins from accumulating in the cytoplasm. Accumulation of unfolded proteins in the cytoplasm can lead to cell death. (en)
rdfs:label
  • GrpE (en)
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