About: Gevotroline

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Gevotroline (WY-47,384) is an atypical antipsychotic with a tricyclic structure which was under development for the treatment of schizophrenia by Wyeth-Ayerst. It acts as a balanced, modest affinity D2 and 5-HT2 receptor antagonist and also possesses high affinity for the sigma receptor. It was well tolerated and showed efficacy in phase II clinical trials but was never marketed.

Property	Value
dbo:abstract	Gevotroline (WY-47,384) is an atypical antipsychotic with a tricyclic structure which was under development for the treatment of schizophrenia by Wyeth-Ayerst. It acts as a balanced, modest affinity D2 and 5-HT2 receptor antagonist and also possesses high affinity for the sigma receptor. It was well tolerated and showed efficacy in phase II clinical trials but was never marketed. (en)
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dbo:chEBI	142391
dbo:fdaUniiCode	7SZ6A2091Q
dbo:pubchem	60547
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dbp:atcPrefix	None (en)
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dbp:casNumber	107266 (xsd:integer)
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dbp:legalStatus	Uncontrolled (en)
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dbp:pubchem	60547 (xsd:integer)
dbp:routesOfAdministration	Oral (en)
dbp:smiles	Fc2cc1c3cCCNCCCc4cccnc4 (en)
dbp:title	dbr:Pharmacodynamics
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rdfs:comment	Gevotroline (WY-47,384) is an atypical antipsychotic with a tricyclic structure which was under development for the treatment of schizophrenia by Wyeth-Ayerst. It acts as a balanced, modest affinity D2 and 5-HT2 receptor antagonist and also possesses high affinity for the sigma receptor. It was well tolerated and showed efficacy in phase II clinical trials but was never marketed. (en)
rdfs:label	Gevotroline (en)
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