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- GRL-0617 is a drug which is one of the first compounds discovered that acts as a selective small-molecule inhibitor of the protease enzyme papain-like protease (PLpro) found in some pathogenic viruses, including the coronavirus SARS-CoV-2. It has been shown to inhibit viral replication in vitro. (en)
- GRL-0617 es un fármaco que es uno de los primeros compuestos descubiertos que actúa como un inhibidor selectivo de molécula pequeña de la proteasa enzima, proteasa similar a la papaína (PLpro) que se encuentra en algunos virus patógenos, incluido el coronavirus SARS-CoV-2. Se ha demostrado que inhibe la replicación viral «in vitro». (es)
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- 3320 (xsd:nonNegativeInteger)
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- CC1=CCN[C@H]C2=CC=CC3=CC=CC=C32 (en)
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- UVERBUNNCOKGNZ-CQSZACIVSA-N (en)
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| rdfs:comment
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- GRL-0617 is a drug which is one of the first compounds discovered that acts as a selective small-molecule inhibitor of the protease enzyme papain-like protease (PLpro) found in some pathogenic viruses, including the coronavirus SARS-CoV-2. It has been shown to inhibit viral replication in vitro. (en)
- GRL-0617 es un fármaco que es uno de los primeros compuestos descubiertos que actúa como un inhibidor selectivo de molécula pequeña de la proteasa enzima, proteasa similar a la papaína (PLpro) que se encuentra en algunos virus patógenos, incluido el coronavirus SARS-CoV-2. Se ha demostrado que inhibe la replicación viral «in vitro». (es)
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| rdfs:label
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- GRL-0617 (en)
- GRL-0617 (es)
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